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  • ===Temperature dependence=== ...olubility in water, but decrease the lipophilicity. This is exploited in [[drug development]] to increase the concentration of a compound in the blood by a
    76 KB (11,861 words) - 20:17, 21 September 2010
  • ...ite book|last=Blandamer|first=M.J.|title=Chemical equilibria in solution : dependence of rate and equilibrium constants on temperature and pressure|publisher=Ell ...m/wps/find/journaldescription.cws_home/30921/description#description|title=Drug discovery today|accessdate=23 March 2010}}</ref>
    42 KB (6,675 words) - 20:17, 21 September 2010
  • ...ant for pharmaceuticals where lipophilicity is a significant property of a drug *Prediction of temperature dependence of lg K values using various thermodynamic models
    38 KB (5,847 words) - 20:17, 21 September 2010
  • In December 2004 the [[Food and Drug Administration]] approved ziconotide [[route of administration|when deliver ...ation. It was approved for sale under the name Prialt by the U.S. Food and Drug Administration on December 28, 2004, and by the [[European Commission]] on
    8 KB (1,082 words) - 22:04, 21 September 2010
  • ...xtended periods of time, physical and [[Substance dependence|psychological dependence]] can develop. ...nd to death but claimed innocence. He was surreptitiously administered the drug, by his [[Lawyer|attorney]], and under the influence of it he revealed why
    9 KB (1,128 words) - 22:04, 21 September 2010
  • '''Tectin''' is the brand name of a [[pain killing drug]] currently in development by [[WEX Pharmaceuticals Inc.]] The drug comes from a toxin in the [[pufferfish]] called [[tetrodotoxin]], a very po
    2 KB (272 words) - 22:05, 21 September 2010
  • Side effects for any drug are difficult to predict, but commonly reported side effects for Fioricet i *[[Substance dependence]]
    3 KB (378 words) - 22:06, 21 September 2010
  • ...pon CB<sub>1</sub> and CB<sub>2</sub> receptor binding. ''Drug and Alcohol Dependence'' 2000; 60:133-140.</ref> However it still displays some weak CB<sub>1</sub ...yl]-(1-naphthalenyl) methanone mesylate, a cannabinoid receptor agonist. ''Drug Metabolism and Disposition''. 2002 Oct;30(10):1077-86. PMID 12228183</ref>
    4 KB (576 words) - 22:08, 21 September 2010
  • ...ng a [[dopamine]] release in the [[nucleus accumbens]]. The effects of the drug can be suppressed by the CB1 [[cannabinoid receptor]] antagonist [[rimonaba | journal = Current Drug Targets-Cns and Neurological Disorders-
    50 KB (6,686 words) - 22:09, 21 September 2010
  • ...ic indoles upon CB(1) and CB(2) receptor binding |journal=Drug and Alcohol Dependence |volume=60 |issue=2 |pages=133–40 |year=2000 |month=August |pmid=10940540
    3 KB (440 words) - 22:10, 21 September 2010
  • ...by heating the flowers and subtending leaves and stems of the [[Cannabis (drug)|Cannabis sativa]] and Indica plants, known as [[marijuana]]. Alternatively ...url=http://www.unodc.org/pdf/WDR_2006/wdr2006_chap2_annex1.pdf|title=World Drug Report|volume=1|id=ISBN 92-1-148214-3|accessdate=2007-11-22|pages=187–192
    12 KB (1,680 words) - 22:10, 21 September 2010
  • {{About|the plant genus|use as a psychoactive drug in the genus|Cannabis (drug)}} ...ychoactive]] molecule that produces the "high" associated with [[cannabis (drug)|marijuana]]. The psychoactive product consists of dried flowers and leaves
    76 KB (10,798 words) - 22:10, 21 September 2010
  • ...am]] for people with common desire to maintain abstinence from [[Cannabis (drug)|marijuana]].<ref name="washtimes">{{cite news|url=|title= Addicted to weed ...>{{cite book|title=A brief cognitive-behavioural intervention for cannabis dependence: Therapists' treatment manual|author=Vaughan Rees, Jan Copeland and Wendy S
    2 KB (298 words) - 22:10, 21 September 2010
  • ...minating the complexities involved in rehabilitation and in treatments for drug addiction. Despite cognitive, social as well as neurological evidence to t ...affective response in marijuana smokers: an fmri study. ''Drug and Alcohol Dependence, 105,'' 139-153.</ref> have been shown in marijuana users. This suggests t
    46 KB (6,708 words) - 22:10, 21 September 2010
  • At one time cannabis was considered a drug that had no withdrawal symptoms because users did not display symptoms simi ...laboratory research has focused on the role of brain chemistry in cannabis dependence. As with other drugs, cannabis increases the production of [[dopamine]], a
    4 KB (577 words) - 22:11, 21 September 2010
  • ...nt services in Australia 2003-04: Report on the national minimum data set. Drug Treatment Series 4. AIHW cat. no. HSE 100 Canberra, Australian Institute of ==Cannabis dependence==
    20 KB (2,835 words) - 22:11, 21 September 2010
  • ...from the hemp plant Cannabis sativa...is the most commonly abused illicit drug in the United States"[http://www.drugabuse.gov/Infofacts/marijuana.html] -- ...ailable in the United Kingdom (UK) | author = Matthew J. Atha (Independent Drug Monitoring Unit)}}</ref>
    72 KB (10,341 words) - 22:11, 21 September 2010
  • ...-Hebert C, Simonpoli AM | year =1997 | month=March | title =[Management of drug addict pregnant women and their children] | journal =Arch Pediatr | volume ...ase anxiety and depression levels in some individuals. In most cases these drug induced psychiatric disorders fade away with prolonged abstinence.<ref>{{ci
    17 KB (2,125 words) - 22:12, 21 September 2010
  • ...the native If/Ih current, but with quantitative differences in the voltage-dependence, activation/deactivation kinetics and sensibility to cAMP: HCN1 channels sh ...themselves. By directly inhibiting HCN channels in vitro, either with the drug ZD7288 or viral knockdown of [[HCN1]] expression, the Arnsten lab was able
    8 KB (1,157 words) - 22:12, 21 September 2010
  • ...ational Cancer Institute, Drug Dictionary]</ref> is an opioid [[medication|drug]] effective against [[diarrhea]] resulting from [[gastroenteritis]] or [[in ...ournal|author=Nakamura H, Ishii K, Yokoyama Y, ''et al.'' |title=[Physical dependence on loperamide hydrochloride in mice and rats] |language=Japanese |journal=Y
    7 KB (989 words) - 22:12, 21 September 2010

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