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• Vasoconstriction
  ...calcium concentration is returned to its basal level through a variety of protein pumps and calcium exchangers located on the plasma membrane and sarcoplasmi ...it|G_i]] --> ↓[[cyclic adenosine monophosphate|cAMP]] --> ↓[[protein kinase A|PKA]] activity --> ↓[[phosphorylation]] of [[myosin light chain
  11 KB (1,498 words) - 21:28, 21 September 2010
• Vasodilation
  ...d, consequently, [[phosphorylation]] of the light chain of the contractile protein [[myosin]]. Thus, vasodilation mainly works either by lowering intracellula | [[Adrenergic]] stimulation results in elevated levels of cAMP and [[protein kinase A]], which results in increasing calcium removal from the cytoplasm
  13 KB (1,665 words) - 21:28, 21 September 2010
• Asymmetric dimethylarginine
  ...d plasma]]. It is a [[metabolism|metabolic]] [[by-product]] of continual [[protein]] modification processes in the [[cytoplasm]] of all human cells. It is clo ...=1992 | title=Endogenous dimethyl-arginine as an inhibitor of nitric oxide synthesis | journal=J. Cardiovasc. Pharmacol | volume=20 |issue=Suppli. 12 | pages=S6
  11 KB (1,513 words) - 21:29, 21 September 2010
• Cannabinoid
  ====Plant synthesis==== ...ion]] techniques. However, to produce high purity cannabinoids, [[chemical synthesis]] or [[semisynthesis]] is generally required.
  49 KB (6,487 words) - 22:06, 21 September 2010
• Endocannabinoid system
  ...oid receptor]]s [[CB1|CB₁]] and [[CB2|CB₂]], two [[G protein-coupled receptors]] primarily located in the central nervous system and per ...ansmitter]]s, endogenous cannabinoids are not stored in [[vesicle]]s after synthesis, but are synthesized on demand (Rodriguez de Fonseca ''et al.'', 2004){{Cit
  23 KB (3,059 words) - 22:08, 21 September 2010
• Tetrahydrocannabinol
  | title = Isolation, structure and partial synthesis of an active constituent of hashish ...receptor type 1|CB₁]] receptor, which is the most abundant [[G protein-coupled receptor]] in the [[brain]].
  50 KB (6,686 words) - 22:09, 21 September 2010
• Neuroproteomics
  '''Neuroproteomics''' is the study of the [[protein]] complexes and species that make up the [[nervous system]]. These protein ...d proteomics was first used in 1994 by Marc Wilkins as the study of “the protein equivalent of a genome” <ref name="pmid16835691">{{cite journal |author=T
  17 KB (2,530 words) - 22:11, 21 September 2010
• Amyloid precursor protein
  ...he X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain | journal = Mol. Cell | volume = 15 | issue = 3 | pages = 343–5 ...et al.| title = Iron-Export Ferroxidase Activity of β- Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease | journal = Cell | year = 2010
  36 KB (4,595 words) - 22:11, 21 September 2010
• Apamin
  {{Infobox protein ...ys15). Because honeybee venom is a complex mixture of short peptides and [[protein]]s, it is difficult to isolate apamin. The isolation can be done by [[elect
  9 KB (1,091 words) - 22:12, 21 September 2010
• Signal transduction
  These processes can take milliseconds (for ion flux), minutes (for protein- and lipid-mediated kinase cascades), hours, or days (for gene expression). ...ysiol.64.082701.102219}}</ref> and bitter and sweet tastes stimulating [[G protein-coupled receptor|taste receptors]] in the [[taste buds]].<ref name=wong>{{c
  55 KB (7,677 words) - 22:12, 21 September 2010
• Fentanyl
  ===Synthesis=== The synthesis of fentanyl [http://cdb.ics.uci.edu/CHEMDB/Web/cgibin/ChemicalDetailWeb.py?
  33 KB (4,684 words) - 21:01, 24 September 2010
• Ketorolac
  ...etorolac acts by [[Enzyme inhibitor|inhibiting]] the [[Biosynthesis|bodily synthesis]] of [[prostaglandins]]. Ketorolac in its oral ([[tablet]] or [[Capsule (p The protein-binding effect of most non-[[aspirin]] NSAIDs are inhibited by the presence
  16 KB (2,012 words) - 22:15, 21 September 2010
• Sulindac
  ...it is thought to act on enzymes COX-1 and COX-2, inhibiting prostaglandin synthesis. Sulindac Inhibits Canonical Wnt Signaling by Blocking the PDZ Domain of the Protein Dishevelled.
  5 KB (722 words) - 22:16, 21 September 2010
• COX-2 inhibitor
  ...d protection of the [[gastrointestinal tract]], while prostaglandins whose synthesis involves the cyclooxygenase-II enzyme, or COX-2, are responsible for inflam ...d to the phosphorylation and activation of the E3 ubiquitin ligase HDM2, a protein that mediates p53 ligation and tagged destruction, through ubiquitination (
  30 KB (4,194 words) - 22:17, 21 September 2010
• Non-steroidal anti-inflammatory drug
  ...absorbed well from the [[stomach]] and intestinal mucosa. They are highly protein-bound in plasma (typically >95%), usually to [[human serum albumin|albumin] ...s the levels of protective [[prostaglandins]]. Inhibition of prostaglandin synthesis in the GI tract causes increased gastric acid secretion, diminished bicarbo
  35 KB (4,649 words) - 22:18, 21 September 2010
• Ethylene
  ...M. T.; Kim-Meade, A. S. "Ethylene" in Encyclopedia of Reagents for Organic Synthesis (Ed: L. Paquette) 2004, J. Wiley & Sons, New York. DOI: 10.1002/047084289.< ...ylene biosynthesis can be induced by endogenous or exogenous ethylene. ACC synthesis increases with high levels of [[auxin]]s, specially [[Indole]] [[acetic aci
  32 KB (4,462 words) - 21:01, 24 September 2010
• Etomidate
  Etomidate is highly protein bound in [[blood plasma]] and is metabolised by hepatic and plasma [[estera ...iated with increased mortality, which is due to suppression of [[steroid]] synthesis (both [[glucocorticoid]]s and [[mineralocorticoid]]s) in the [[adrenal cort
  10 KB (1,350 words) - 21:01, 24 September 2010
• Xenon
  ...exafluoride|{{chem|XeF|6}}]]. The fluorides are the starting point for the synthesis of almost all xenon compounds. |title=Synthesis, Properties and Chemistry of Xenon(II) Fluoride|journal=Acta Chimica Sloven
  82 KB (11,842 words) - 21:02, 24 September 2010
• Propofol
  Propofol is highly protein-bound ''in vivo'' and is metabolised by [[Xenobiotic conjugation|conjugatio ...nco M, Altomare C, Sanna E, Usala M, Biggio G, Liso G. Propofol analogues. Synthesis, relationships between structure and affinity at GABA_A receptor
  21 KB (2,875 words) - 21:03, 24 September 2010
• Gamma-Hydroxybutyric acid
  Synthesis of the chemical GHB was first reported in 1874 by [[Alexander Mikhaylovich ...ncrease extracellular glutamate in the hippocampus, but fail to activate G protein and to produce the sedative/hypnotic effect of gamma-hydroxybutyric acid |j
  55 KB (7,839 words) - 21:04, 24 September 2010
• Rendering (food processing)
  ...ow grease]], choice white grease, bleachable fancy [[tallow]], etc.) and a protein meal ([[meat & bone meal]], poultry byproduct meal, etc.). ...n into a [[sanitary sewer|sewer]] or it was evaporated to make [[glue]] or protein concentrate to add to [[fertilizer]]. The solids were used to make fertili
  16 KB (2,490 words) - 19:39, 13 October 2010

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