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- ...an activate and influence biochemical behaviour of most cells. The steroid/receptor complexes dimerise and interact with cellular DNA in the nucleus, binding t7 KB (872 words) - 16:41, 27 September 2010
- ...INR should be monitored closely. They may also interact with the [[GABA A receptor]] and cause neurological symptoms; this effect is augmented by certain [[no88 KB (11,930 words) - 16:46, 27 September 2010
- ...the experiments in rats, via the action on [[arachidonic acid]] and [[NMDA receptor]]s cascade.<ref name="Gutton">{{Cite journal|author=Guitton MJ, Caston J, R78 KB (10,918 words) - 16:52, 27 September 2010
- ...enolol''' ('''Tenormin''') is a selective [[beta-1 receptor|β<sub>1</sub> receptor]] [[receptor_antagonist|antagonist]], a [[drug]] belonging to the group of ...lpha-agonists (e.g. [[clonidine]]), [[ACE Inhibitor]]s or [[Angiotensin II receptor antagonist]]s such as losartan can also be given additionally. Exert cautio12 KB (1,720 words) - 16:48, 27 September 2010
- ...development, the α<sub>6</sub>β<sub>2</sub>γ<sub>2</sub> receptor increases in expression in cerebellar granule neurons, corresponding to inc12 KB (1,678 words) - 16:48, 27 September 2010
- ...D<sub>3</sub>]], [[Dopamine D4 receptor|D<sub>4</sub>]], and [[Dopamine D5 receptor|D<sub>5</sub>]]—and their variants. Dopamine is produced in several areas Via the [[dopamine receptor]]s, D<sub>1-5</sub>, dopamine reduces the influence of the indirect pathway48 KB (6,470 words) - 16:48, 27 September 2010
- '''Timolol maleate''' is a non-selective [[beta blocker|beta-adrenergic receptor blocker]]. In its oral form ('''Blocadren'''), it is used to treat [[hypert4 KB (476 words) - 16:46, 19 September 2010
- ...short-acting [[beta2-adrenergic receptor agonist|β<sub>2</sub>-adrenergic receptor agonist]] used for the relief of [[bronchospasm]] in conditions such as [[a Salbutamol was the first selective Β2-receptor agonist to be marketed — in 1968. It was first sold by Allen & Hanburys u15 KB (2,005 words) - 16:49, 27 September 2010
- ...s Type I and Type II receptor agonist), or [[RU28362]] (a specific Type II receptor agonist), to adrenalectomized animals induced changes in [[leukocyte distri .... Aldosterone and cortisol have similar affinity for the mineralocorticoid receptor however, glucocorticoids circulate at roughly 100 times the level of minera41 KB (5,644 words) - 16:50, 27 September 2010
- {{See also|Adrenergic receptor}} ...ues. Its actions vary by tissue type and tissue expression of [[adrenergic receptor]]s. For example, epinephrine causes [[smooth muscle]] relaxation in the air22 KB (2,916 words) - 16:50, 27 September 2010
- ...and slightly potentiates [[GABAA receptor|GABA<sub>A</sub>]] and [[glycine receptor]]s.<ref name="pmid11020766">{{cite journal|author = Yamakura T, Harris RA|t ...7862891}}</ref> Indeed, in humans given 30% N<sub>2</sub>O, benzodiazepine receptor antagonists reduced the subjective reports of feeling "high", but did not a61 KB (8,728 words) - 16:50, 27 September 2010
- ...that apparently only reacted to morphine: the mu3 [[Opioid receptor|opiate receptor]] in human tissue.<ref>{{cite journal |author=Zhu W, Cadet P, Baggerman G, ...de release in the mammalian gastrointestinal tract via the micro(3) opiate receptor subtype: a hormonal role for endogenous morphine|journal=Journal of Physiol87 KB (12,376 words) - 16:51, 27 September 2010
- ...inding to the benzodiazepine site on the [[GABAA receptor|GABA<sub>A</sub> receptor]] leading to [[central nervous system]] depression.<ref name="Riss-2008"/> ...irst2 = R. | last3 = Hösl | first3 = K. | title = Subtype-selective GABAA receptor mimetics--novel antihyperalgesic agents? | url = http://www.springerlink.co78 KB (10,295 words) - 16:51, 27 September 2010
- ...nn M"/> 3) Surface enterocytes also express high levels of [[Interleukin-1 receptor]] (IL-1R) -containing inhibitory molecule. IL-1R are also referred to as si ...mponent that monitors and responds to changes in the environment. When the receptor senses a stimulus, it sends information to a '''control center''', the comp21 KB (3,070 words) - 21:41, 19 September 2010
- ...url=}}</ref> There is some evidence that it may act at [[Beta-3 adrenergic receptor|β<sub>3</sub> adrenergic receptors]].<ref name="pmid10344530">{{cite journ7 KB (919 words) - 13:14, 20 September 2010
- ...ction there. The cytokine factors then bind with [[endothelium|endothelial receptor]]s on vessel walls, or interact with local [[microglial cell]]s. When these ...ein]] (LBP) binds to LPS. The LBP–LPS complex then binds to the [[CD14]] receptor of a nearby [[macrophage]]. This binding results in the synthesis and relea27 KB (3,703 words) - 20:20, 20 September 2010
- ...[[Complement Receptor 3|Macrophage-1 antigen]] ([[CD18]]) [[cell receptor|receptor]] on immune cells.<ref name=pmid15084502>{{cite pmid|15084502}} (review)</r ...recent{{When|date=May 2010}} study reported that the [[selective estrogen receptor modulator]] [[raloxifene]] has similar benefits to [[tamoxifen]] in prevent94 KB (13,321 words) - 21:32, 20 September 2010
- ...i, C; Cacciarini, M; Pergoli, R; Roelens, S|date=2004|title=A New Tripodal Receptor for Molecular Recognition of Monosaccharides. A Paradigm for Assessing Glyc50 KB (7,450 words) - 20:16, 21 September 2010
- ...biochemistry]] host-guest complexes are known as [[receptor (biochemistry)|receptor]]-ligand complexes; they are formed primarily by [[non-covalent bond]]ing. ...ther blocks a receptor, an [[antagonist]] which forms a strong complex the receptor, or activate it, an [[agonist]], is an important pathway to [[drug discover42 KB (6,675 words) - 20:17, 21 September 2010
- ...eriodic syndrome]] (Familial Hibernian fever, TRAPS, Tumor necrosis factor receptor associated periodic syndrome) *[[Leukotriene receptor antagonist-associated Churg–Strauss syndrome]]177 KB (19,269 words) - 21:05, 21 September 2010
- * [[Hypercholesterolemia due to LDL receptor deficiency]] * [[Hyperthyroidism due to mutations in TSH receptor]]19 KB (1,633 words) - 21:07, 21 September 2010
- * [[Mutations in estradiol receptor]]26 KB (2,392 words) - 21:07, 21 September 2010
- * [[Complement component receptor 1]]37 KB (3,368 words) - 21:07, 21 September 2010
- | Dihydrotestosterone receptor deficiency <br><small>''see'' [[androgen insensitivity syndrome]] </small>65 KB (7,342 words) - 21:07, 21 September 2010
- ...a gravis]]* results from the presence of antibodies to the [[acetylcholine receptor]]. Signs include [[megaesophagus]] and muscle weakness.<ref>{{cite web | ti99 KB (14,444 words) - 21:22, 3 October 2011
- ...calcium channel blockers (i.e. verapamil, deltiazem, nifedipine) and Beta-receptor antagonists (i.e. propranolol). Beta-receptor antagonists do not cause vasodilation but they do decrease the heart's dema7 KB (957 words) - 21:27, 21 September 2010
- !Receptor <br/> (↑ = opens. ↓ = closes) <ref name=boron/> <br> <font size=1> On [ |rowspan=2| [[nitric oxide]] || ↑[[NO receptor]] on smooth muscle || ↑[[cyclic GMP|cGMP]] --> ↑[[protein kinase g|PKG]13 KB (1,665 words) - 21:28, 21 September 2010
- ..., into the [[sarcoplasm]] of muscle cell. Calcium ions bind to [[ryanodine receptor]]s on the [[sarcoplasmic reticulum]] causing a flux of calcium ions to the10 KB (1,375 words) - 21:29, 21 September 2010
- ...tp://www.nature.com/bjp/journal/v143/n4/full/0705974a.html "Selective GABA-receptor actions of amobarbital on thalamic neurons."] ''British Journal of Pharmaco ...hader RI | title=Acute barbiturate administration increases benzodiazepine receptor binding in vivo | journal=Psychopharmacology (Berl) | volume=96 | issue=3 |9 KB (1,128 words) - 22:04, 21 September 2010
- ...the [[Alpha-4 beta-2 nicotinic receptor|α4β2]] [[nicotinic acetylcholine receptor#Subunits|subtypes]]. It was developed as a less toxic [[analog (chemistry)|2 KB (271 words) - 22:05, 21 September 2010
- ...nic acetylcholine receptor]]s selective for the [[Alpha-4 beta-2 nicotinic receptor|α4β2]] subtype, and has been researched for use as an [[analgesic]], alth1 KB (131 words) - 22:06, 21 September 2010
- ...brain: isolation, structure elucidation, and interactions with the opiate receptor |journal=Proc Natl Acad Sci USA |volume=73 |issue=7 |pages=2515–9 |year=1 ...for the κ<sub>1</sub> opioid receptors. μ opioid receptors are the main receptor through which [[morphine]] acts. Classically, μ opioid receptors are presy18 KB (2,467 words) - 22:06, 21 September 2010
- ...nti-inflammatory action is induced through the activation of [[cannabinoid receptor]]s which prevents [[microglia]]l activation that elicits the inflammation.5 KB (653 words) - 22:07, 21 September 2010
- ...Tomasini MC, Gessa GL, Bebe BW, Tanganelli S, Antonelli T. The Cannabinoid Receptor Agonist WIN 55,212-2 Regulates Glutamate Transmission in Rat Cerebral Corte ...t.'' 1997 '''221''' 157</ref>. It activates p42 and p44 [[MAP kinase]] via receptor-mediated signaling.<ref>M. Bouaboula ''et al. Biochem. J.'' 1995 '''312'''4 KB (544 words) - 22:08, 21 September 2010
- ...3.4nM and selectivity of around 200x for CB<sub>2</sub> over [[Cannabinoid receptor type 1|CB<sub>1</sub>]] receptors. It was discovered by, and named after, [ ...antiinflamatory action is induced through agonist action at [[cannabinoid receptor]]s, which prevents [[microglia]]l activation that elicits the inflammation.3 KB (360 words) - 22:08, 21 September 2010
- ...bind to the centrally expressed cannabinoid receptor type-1 ([[Cannabinoid receptor 1|CB<sub>1</sub>]]) and therefore does not exert psychomimetic effects.12 KB (1,566 words) - 22:09, 21 September 2010
- ...cannabinoid receptors]], acting as an [[inverse agonist]] at [[Cannabinoid receptor 1|CB<sub>1</sub>]] receptors.<ref name="pmid18077343">{{cite journal |autho6 KB (800 words) - 22:09, 21 September 2010
- ...nabidiol modulates and directly activates alpha-1 and alpha-1-Beta glycine receptor function|journal = [[Pharmacology]]|volume = 83|issue = 4|pages = 217–222 ...acting on a [[cannabinoid receptor]] on the [[ciliary body]] called the CB receptor.<ref>{{cite journal|author = Goldberg J, Flowerdew G, Smith E, Brody JA, Ts76 KB (10,798 words) - 22:10, 21 September 2010
- ...ub>]], [[GABAA-rho receptor|GABA<sub>A</sub>-ρ]], [[glycine]] and [[5-HT3 receptor|5-HT<sub>3</sub> receptors]] that are composed of five [[protein subunit]]s ...e journal | author = Sine S, Engel A | title = Recent advances in Cys-loop receptor structure and function. | journal = Nature | volume = 440 | issue = 7083 |2 KB (312 words) - 22:11, 21 September 2010
- :{{Main|Nerve growth factor receptor}} There are two classes of [[receptor (biochemistry)|receptor]]s for neurotrophins: p75 and the "Trk" family of [[Tyrosine kinase]]s rece9 KB (1,202 words) - 22:11, 21 September 2010
- ...comparisons to the signaling role of the surface [[transmembrane receptor|receptor]] protein [[Notch signaling|Notch]].<ref name="Selkoe">{{cite journal | aut *{{cite journal | author=Coulson EJ |title=Does the p75 neurotrophin receptor mediate Abeta-induced toxicity in Alzheimer's disease? |journal=J. Neuroche36 KB (4,595 words) - 22:11, 21 September 2010
- ...hormone]] on its target. The hormone activates or deactivates [[ionotropic receptor]]s (ligand-gated ion channels). The effect can be either positive or negati ...ionotropic effect on [[heart muscle]], when binding to [[beta-1 adrenergic receptor]]s on this tissue<ref name=purves> Neuroscience (Purves), Third Edition, ta766 bytes (96 words) - 22:12, 21 September 2010
- ...=|accessdate=}}</ref> Signal transduction starts with a signal to a receptor, and ends with a change in cell function. ...de the cell. The chemical signal binds to the outer portion of the receptor, changing its shape and conveying another signal inside the cell. So55 KB (7,677 words) - 22:12, 21 September 2010
- *Some [[transient receptor potential channel]]s: This group of channels, normally referred to simply a ...nion-permeable γ-aminobutyric acid-gated [[GABA receptor|GABA<sub>A</sub> receptor]].31 KB (4,177 words) - 22:12, 21 September 2010
- ...els''' ('''LGICs''') are one type of ionotropic receptor or channel-linked receptor. They are a group of [[transmembrane]] [[ion channel]]s that are opened or ...tle = The Cys-loop superfamily of ligand-gated ion channels: the impact of receptor structure on function | journal = Biochem. Soc. Trans. | volume = 32 | issu17 KB (2,344 words) - 22:12, 21 September 2010
- ...hydromorphone, related to the morphine molecule, is a primary [[mu opioid receptor|μ]] agonist]. Although this can lead to addiction and reward-seeking behav Hydromorphone, a semi-synthetic [[Opioid receptor#The μ-opioid receptor|μ-opioid]] [[agonist]], is a [[hydrogenation|hydrogenated]] [[ketone]] of38 KB (5,300 words) - 22:13, 21 September 2010
- ...8}}</ref> In addition, it is a synthetic strong agonist at the [[mu opioid receptor|μ-opioid]] receptors. Historically it has been used to treat [[breakthroug33 KB (4,684 words) - 21:01, 24 September 2010
- ...lly unlike [[morphine]] or [[heroin]], methadone also acts on the [[opioid receptor]]s and thus produces many of the same effects. Methadone is also used in ma ...receptor, but also has some affinity for the [[NMDA]] ionotropic glutamate receptor. It is metabolized by the enzymes [[CYP3A4]], [[CYP2B6]] and [[CYP2D6]], wi61 KB (8,865 words) - 22:13, 21 September 2010
- ...Receptor antagonist|antagonist]] of N-methyl-d-aspartate receptors ([[NMDA receptor]]s). These receptors exacerbate the damage from [[oxygen deprivation]] and [[Category:NMDA receptor antagonists]]82 KB (11,842 words) - 21:02, 24 September 2010
- ...0s by Dr. [[Henri Laborit]] to use in studying the neurotransmitter [[GABA receptor|GABA]].<ref>{{cite journal | author = H. Laborit, J.M. Jouany, J. Gerald, F ...}</ref> and it is a weak agonist at the [[GABA receptor|GABA<sub>B</sub>]] receptor, which is [[inhibitory]].<ref name="mechanism" /> GHB is a naturally-occurr55 KB (7,839 words) - 21:04, 24 September 2010