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- ...Merck; while Huff and his associates confirmed that mevalonic acid was an intermediate in cholesterol biosynthesis. In 1959, the [[HMG-CoA reductase]] enzyme (a m ...terms of lipid lowering. There is also evidence of raising [[high density lipoprotein]] (HDL) and lowering [[triglyceride]] (TG) levels.14 KB (1,967 words) - 16:48, 27 September 2010