Talopram

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Talopram
File:Talopram.png
Systematic (IUPAC) name
3-(3,3-dimethyl-1-phenyl-isobenzofuran-1-yl)-N-methyl-propan-1-amine
Identifiers
CAS Number 7182-51-6
ATC code none
PubChem CID 23573
ChemSpider 22042
Chemical data
Formula C20H25NO
Molar mass 295.42 g/mol[[Script error: No such module "String".]]
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Talopram (Lu 3-010), also known as phthalapromine, is a selective norepinephrine reuptake inhibitor (NRI) which was researched for the management of depression in the 1960s and 1970s but was never commercialized.[1] Along with talsupram, it is structurally related to the selective serotonin reuptake inhibitor (SSRI) citalopram.[2]

See also

References

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  1. Eildal JN, Andersen J, Kristensen AS, Jørgensen AM, Bang-Andersen B, Jørgensen M, Strømgaard K. From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram: synthesis and structure-activity relationship studies. J Med Chem. 2008 May 22;51(10):3045-8. PMID 18429609
  2. Eildal JN, Andersen J, Kristensen AS, Jørgensen AM, Bang-Andersen B, Jørgensen M, Strømgaard K. From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram: synthesis and structure-activity relationship studies. J Med Chem. 2008 May 22;51(10):3045-8. PMID 18429609