Template:PBB/3976

Leukemia inhibitory factor (cholinergic differentiation factor)
250px PDB rendering based on 1LKI.
Available structures PDB 1emr, 1lki, 1pvh
Identifiers
Symbols	LIF; CDF; D-FACTOR; HILDA
External IDs	OMIM: 159540 MGI: 96787 HomoloGene: 1734 GeneCards: LIF Gene
Gene Ontology Molecular function • cytokine activity • leukemia inhibitory factor receptor binding • oncostatin-M receptor binding • growth factor activity Cellular component • extracellular region • extracellular space Biological process • immune response • cell surface receptor linked signal transduction • cell-cell signaling • multicellular organismal development • positive regulation of cell proliferation • tyrosine phosphorylation of Stat3 protein • muscle morphogenesis • neuron development Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3976	16878
Ensembl	ENSG00000128342	ENSMUSG00000034394
UniProt	P15018	Q3U1H5
RefSeq (mRNA)	NM_002309	NM_001039537
RefSeq (protein)	NP_002300	NP_001034626
Location (UCSC)	Chr 22: 28.97 - 28.97 Mb	Chr 11: 4.16 - 4.17 Mb
PubMed search	[1]	[2]