Xylazine

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Xylazine
File:Xylazin.svg
Systematic (IUPAC) name
N-​(2,6-​dimethylphenyl)-​5,6-​dihydro-​4H-​1,3-​thiazin-​2-​amine
Legal status
Legal status
  • Veterinary Use
Identifiers
CAS Number 7361-61-7
ATCvet code QN05CM92 (WHO)
PubChem CID 5707
IUPHAR/BPS 523
Chemical data
Formula C12H16N2S
Molar mass 220.33[[Script error: No such module "String".]]
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Xylazine is a drug that is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. An analogue of clonidine, it is an agonist at the α2 class of adrenergic receptor. As with other α2 agonists, adverse effects include bradycardia, conduction disturbances, and myocardial depression. Yohimbine (Yobine) and atipamezole (commercial name Antisedan) can be used to reverse xylazine effects. In veterinary anesthesia, xylazine is often used in combination with ketamine. No formal information in humans is available. Xylazine is sold by Bayer under the brand name Rompun.

Veterinary Indications

Veterinarians use xylazine as an emetic when it is desirable to remove a substance from a cat's stomach. In one trial, pilocarpine was used instead of xylazine.


References



de:Xylazin

fr:Xylazine it:Xilazina ja:キシラジン ru:Ксилазин