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Ball-and-stick model of ethane-1,2-dithiol
Space-filling model of ethane-1,2-dithiol
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number 540-63-6 YesY
ChemSpider 13865015
RTECS number KI3325000
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InChI Script error: No such module "collapsible list".
style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula C2H6S2
Molar mass 94.20 g/mol
Appearance Colorless liquid
Density 1.123 g/cm³, liquid
Melting point

-41 °C

Boiling point

146 °C
63 °C @46 mmHg

Solubility in water Slightly sol
Solubility in other solvents Good solubility in
most organic solvents
Acidity (pKa) ~11
Refractive index (nD) 1.5589 (D-line, 25 °C)
style="background: #F8EABA; text-align: center;" colspan="2" | Hazards
EU classification Toxic (T)
R-phrases R10 R22
S-phrases S16
NFPA 704
Flash point 50 °C
style="background: #F8EABA; text-align: center;" colspan="2" | Related compounds
Related thiols Ethanethiol; 1,3-Propanedithiol; 1,2-Benzenedithiol; Thiophenol
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

1,2-Ethanedithiol is an odorous, colorless liquid with the formula C2H4(SH)2. It has a very characteristic odour which is compared by many people to rotten cabbage. It is a common building block in organic synthesis and an excellent ligand for metal ions.


1,2-Ethanedithiol is commercially available. It can be prepared by the action of 1,2-dibromoethane on thiourea followed by hydrolysis.[1]


This compound is widely used in organic chemistry because it reacts with aldehydes and ketones to give 1,3-dithiolanes, which are useful intermediates. [2]

C2H4(SH)2 + RR'CO → C2H4S2CRR' + H2O

Other 1,2- and 1,3-dithiols undergo this reaction to give related 1,3-dithiolanes and 1,3-dithianes (six-membered rings). Diols such as ethylene glycol undergo analogous reactions to 1,3-dioxalanes and 1,3-dioxanes. One distinguishing feature of the dithiolanes and dithianes derived from aldehydes is that the methyne group can be deprotonated and the resulting carbanion alkylated.


  1. Speziale, A. J. (1963), "Ethanedithiol", Org. Synth. ; Coll. Vol., 4: 401  Missing or empty |title= (help)
  2. R. E. Conrow "Ethanedithiol" in Encyclopedia of Reagents for Organic Synthesis (Ed: L. Paquette) 2004, J. Wiley & Sons, New York. DOI: 10.1002/047084289.

ja:1,2-エタンジチオール zh:乙二硫醇