Amikhelline

Amikhelline
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Systematic (IUPAC) name
	9-(2-diethylaminoethoxy)-4-hydroxy-7-methylpyrano[3,2-f][1]benzoxol-5-one
Pharmacokinetic data
Metabolism	none
Identifiers
CAS Number	4439-67-2
ATC code	none
PubChem	CID 71198
ChemSpider	64334
Chemical data
Formula	C18H21NO5
Molar mass	331.363 g/mol[[Script error: No such module "String".]]
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Amikhelline is an antimitotic drug.^[1] It acts as a DNA intercalator^[2] and inhibits DNA polymerase.^[3]

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References

↑ Turchini MF, Geneix A, Perissel B, Malet P, Turchini JP. Characterization of chromosomal aberrations induced in man by various antimitotic agents. (French). Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales. 1985;179(3):331-9. PMID 2417673
↑ Rucheton M, Jeanteur P. Studies on amikhellin. I. Intercalative binding to double-stranded DNA. Biochimie. 1973;55(11):1415-20. PMID 4364376
↑ Rucheton M, Jeanteur P. Studies on amikhellin. II.-Inhibition of dna-polymerase from murine sarcoma leukemia virus. Biochimie. 1976;58(6):689-95. PMID 60141