Azoxystrobin

From Self-sufficiency
Jump to: navigation, search
Azoxystrobin
File:Azoxystrobine.png
File:Azoxystrobin-from-xtal-3D-balls.png
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number 131860-33-8 YesY
PubChem 3034285
ChemSpider 2298772
SMILES Script error: No such module "collapsible list".
InChI Script error: No such module "collapsible list".
InChI key WFDXOXNFNRHQEC-GHRIWEEIBD
style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula C22H17N3O5
Molar mass 403.39 g mol−1
 YesY (what is this?)  (verify)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Azoxystrobin is a fungicide commonly used in agriculture. The substance is used as an active agent protecting plants and fruit/vegetables from fungal diseases.

Origin

Azoxystrobin was discovered during research on Oudemansiella mucida and Strobilurus tenacellus, which are small white or brown coloured mushrooms commonly found in the Czech forests. Not bigger than a few centimeters, these mushrooms attracted attention of scientists because of their remarkable ability to defend themselves. Their defense mechanism is based on the secretion of two substances, strobilurin A and oudemansin A. These substances allow them to keep their competitors at a distance and even destroy them when in range. Observations of this mechanism led directly to research that resulted in azoxystrobin.

Activity

After synthesizing experimental analogs of both substances (over 1400 were tested), azoxystrobin was found to be the most active and stable combination. The pharmacophore of azoxystrobine is the β-methoxyacrylate portion, which is present in the active compounds from both Oudemansiella mucida and Strobilurus tenacellus.

Efficiency

Azoxystrobin possesses the broadest spectrum of activity of all presently known antifungals. It is presently the only counteragent that has the ability to protect against the 4 big groups of fungal diseases:

Examples

Azoxystrobin is widely used in farming, particularly in wheat farming. Applying agents containing azoxystrobin provides protection against many types of diseases, including:

Practical use

  • Grain farming
  • Banana transport
  • grapes, both table & wine

Ecotoxicology

Azoxystrobin has a favorable ecotoxicological profile, meeting the expectations of agricultural demand.

Its toxicity is low for mammals, birds, bees, insects, and earthworms. It is highly toxic for freshwater fish and invertebraes and very highly toxic for marine invertebraes. (this is disputed. Please read discussion page for details)

Azoxystrobin is broken down into the soil. The agent is not very mobile and therefore is unlikely to penetrate further in the soil and come into contact with groundwater.

External links

nl:Azoxystrobin