Bromfenac
From Self-sufficiency
| File:Bromfenac.png | |
| Systematic (IUPAC) name | |
|---|---|
|
2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid | |
| Clinical data | |
| Pregnancy category |
|
| Routes of administration |
Oral (discontinued) ophthalmic |
| Legal status | |
| Legal status |
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| Identifiers | |
| CAS Number | 91714-94-2 |
| ATC code | S01BC11 (WHO) |
| PubChem | CID 60726 |
| Chemical data | |
| Formula | C15H12BrNO3 |
| Molar mass | 334.16g/mol[[Script error: No such module "String".]] |
| (verify) | |
Bromfenac is a non-steroidal anti-inflammatory drug (NSAID) marketed in the US as an ophthalmic solution (brand name Xibrom) by Ista for short-term, local use.
It was originally introduced as a prescription capsule (brand name Duract) by Wyeth=-Ayerst, but this form of the drug was withdrawn from the US market and discontinued due to side effects of systemic, long-term administration.
Chemistry
Walsh, David A.; Moran, H. Wayne; Shamblee, Dwight A.; Uwaydah, Ibrahim M.; Welstead, William J.; Sancilio, Lawrence F.; Dannenburg, Warren N. (1984). "Antiinflammatory agents. 3. Synthesis and pharmacological evaluation of 2-amino-3-benzoylphenylacetic acid and analogs". Journal of Medicinal Chemistry. 27 (11): 1379. doi:10.1021/jm00377a001. PMID 6436487.
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- Non-steroidal anti-inflammatory drugs
- Aromatic amines
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- Organobromides
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