Copper ibuprofenate

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Copper ibuprofenate
File:Copper ibuprofenate.png
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number 66840-44-6
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style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula C26H36CuO4
Molar mass 476.11 g mol−1
Appearance Green powder
Solubility in water Slightly soluble
Solubility in isopropanol Slightly soluble
style="background: #F8EABA; text-align: center;" colspan="2" | Related compounds
Related compounds Copper aspirinate

Ibuprofen

Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Copper ibuprofenate is a chemical complex consisting of copper(II) and the anionic form of the anti-inflammatory drug ibuprofen.[1][2][3]

Usage

Research has suggested that copper complexes of anti-inflammatory drugs are more active than the drug by itself,[1][4] and produce fewer gastrointestinal side-effects.[5] In 2008, a United States patent was issued for the utilization of ibuprofenate complexes (including copper ibuprofenate) as a wood preservative.[6][7]

References

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  1. 1.0 1.1 A. Latif, Abuhijleh (1997). "Synthesis and characterization of copper-ibuprofenate complexes with 2,2'-bipyridine and 1,10-phenanthrolines and their hydrolytic activities in phosphate diester cleavage". Polyhedron. 16 (4): 733–740. doi:10.1016/0277-5387(96)00214-8. 
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  4. Sorenson JR (1989). "Copper complexes offer a physiological approach to treatment of chronic diseases". Prog Med Chem. 26: 437–568. PMID 2690187. 
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  6. "Ibuprofen complexes as wood preservatives - US pat. no, 7,462,227". US Patent Office. Retrieved 1 February 2010. 
  7. "US Patent 7462227 - Ibuprofen complexes as wood preservatives". Patent Storm. Retrieved 1 February 2010.