Delafloxacin
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File:Delafloxacin.svg | |
Systematic (IUPAC) name | |
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1-(6-amino-3,5-difluoro-2-pyridyl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-quinoline-3-carboxylic acid | |
Legal status | |
Legal status |
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Identifiers | |
CAS Number | 189279-58-1 |
ATC code | none |
PubChem | CID 487101 |
ChemSpider | 427049 |
Chemical data | |
Formula | C18H12ClF3N4O4 |
Molar mass | 440.76 g/mol[[Script error: No such module "String".]] |
Script error: No such module "collapsible list". |
Delafloxacin (originally RX-3341) is a fluoroquinolone antibiotic being developed by Rib-X Pharmaceuticals, Inc.
It is more active (lower MIC90) than other quinolones against Gram-positive bacteria such as MRSA.
Phase II clinical trials have reported good results.[1][2][3] for example compared with tigecycline[4]
References
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- ↑ http://www.bio-medicine.org/biology-technology-1/Rib-X-Pharmaceuticals-Announces-Positive-Phase-2-Study-Results-for-Delafloxacin-and-a--2425-Million-Financing-10093-1/
- ↑ http://clinicaltrials.gov/ct2/show/NCT00719810
- ↑ http://www.medicalnewstoday.com/articles/132200.php "Rib-X Pharmaceuticals Reports Positive Top-Line Results From Phase 2 Study Of Delafloxacin" 9 Dec 2008
- ↑ http://www.citybizlist.com/lstg/lstgDetail.aspx?id=45749 "ABS Ventures Joins $25M Series D Rib-X Pharmaceuticals Inc." 5 Feb 2009
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