Dressler's syndrome
| Dressler's syndrome | |
|---|---|
| Classification and external resources | |
| ICD-10 | I24.1 |
| ICD-9 | 411.0 |
| DiseasesDB | 3947 |
Dressler's syndrome is a secondary form of pericarditis that occurs in the setting of injury to the heart or the pericardium (the outer lining of the heart).
Dressler's syndrome is also known as postmyocardial infarction syndrome[1] and the term is sometimes used to refer to post-pericardiotomy pericarditis.
It was first characterized by William Dressler in 1956.[2][3][4]
It should not be confused with the Dressler's syndrome of haemoglobinuria named for Lucas Dressler, who characterized it in 1854.[5][6]
Presentation
Dressler's syndrome is largely a self limiting disease that very rarely leads to pericardial tamponade. The syndrome consists of a persistent low-grade fever, chest pain (usually pleuritic in nature), a pericardial friction rub, and /or a pericardial effusion. The symptoms tend to occur 2 weeks post myocardial infarction, but can be delayed for a few months after infarction. It tends to subside in a few days. An elevated ESR is an objective laboratory finding.
Causes
It is believed to result from an autoimmune inflammatory reaction to myocardial neo-antigens.
Dressler's syndrome is associated with myocardial infarction (heart attack). A similar pericarditis can be associated with any pericardiotomy or trauma to the percardium or heart surgery.
Differential diagnosis
In the setting of myocardial infarction, Dressler's syndrome occurs in about 7% of cases,[7] and typically occurs several weeks after the myocardial infarction has occurred (cited from Robbins and Cotran 8th edition). Dressler's syndome is also known as post-myocardial infarction syndrome, post-cardiac injury syndrome and postpericardiotomy syndrome. Dressler's syndrome needs to be differentiated from pulmonary embolism, another identifiable cause of pleuritic (and non-pleuritic) chest pain in people who have been hospitalized and/or undergone surgical procedures within the preceding weeks.
Treatment
Dressler's syndrome is typically treated with NSAIDs such as aspirin or with corticosteroids.[8] However corticosteroids are reserved for rare cases and are seldom required.
References
Cite error: Invalid <references> tag;
parameter "group" is allowed only.
<references />, or <references group="..." />External links
de:Dressler-Syndromes:Síndrome de Dressler fa:نشانگان درسلر pl:Zespół Dresslera pt:Síndrome de Dressler
ru:Постинфарктный синдром- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
- ↑ synd/3982 at Who Named It?
- ↑ L. A. Dressler. Ein Fall von intermittirender Albuminurie und Chromaturie. Archiv für pathologische Anatomie und Physiologie und für klinische Medicin, 1854, 6: 264-266.
- ↑ Krainin F, Flessas A, Spodick D (1984). "Infarction-associated pericarditis. Rarity of diagnostic electrocardiogram". N Engl J Med. 311 (19): 1211–4. doi:10.1056/NEJM198411083111903. PMID 6493274.
- ↑ Gregoratos G (1990). "Pericardial involvement in acute myocardial infarction". Cardiol Clin. 8 (4): 601–8. PMID 2249214.
