End-systolic volume

End-systolic volume (ESV) is the volume of blood in a ventricle at the end of contraction, or systole, and the beginning of filling, or diastole.

ESV is the lowest volume of blood in the ventricle at any point in the cardiac cycle. The main factors that affect the end-systolic volume are afterload and the contractility of the heart.

Uses

End systolic volume can be used clinically as a measurement of the adequacy of cardiac emptying, related to systolic function. On an electrocardiogram, or ECG, the end-systolic volume will be seen at the end of the T wave. Clinically, ESV can be measured using two-dimensional echocardiography, MRI (magnetic resonance tomography) or cardiac CT (computed tomography).

Sample values

Along with end-diastolic volume, ESV determines the stroke volume, or output of blood by the heart during a single phase of the cardiac cycle. The stroke volume is the difference between the end-diastolic volume and the end-systolic volume.

Measure	Typical value
end-diastolic volume (EDV)	120 ml
end-systolic volume (ESV)	50 ml
stroke volume (SV)	55 - 100 ml
ejection fraction (Ef)	58%
heart rate (HR)	72 bpm
cardiac output (CO)	4.9 L/minute