Ertumaxomab

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Ertumaxomab
Monoclonal antibody
Type Trifunctional antibody
Source Template:Infobox drug/mab source
Target HER2/neu, CD3
Identifiers
CAS Number 509077-99-0
ATC code none
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Ertumaxomab (trade name Rexomun) is a rat-murine hybrid monoclonal antibody designed to treat some types of cancer. As of September 2009, a Phase II clinical trial evaluating the treatment of breast cancer is recruiting participants.[1]

It is a so-called trifunctional antibody which works by linking T-lymphocytes and macrophages to the cancer cells.[2]

References

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  1. ClinicalTrials.gov: Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer After Progression on Trastuzumab Therapy
  2. Fresenius