Gingerol
| Gingerol | |
|---|---|
| Gingerol | |
| (S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone | |
| style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers | |
| CAS number | 23513-14-6 |
| SMILES | Script error: No such module "collapsible list". |
| style="background: #F8EABA; text-align: center;" colspan="2" | Properties | |
| Molecular formula | C17H26O4 |
| Molar mass | 294.38 g/mol |
| Melting point |
30-32 °C |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
Gingerol, or sometimes [6]-gingerol, is the active constituent of fresh ginger. Chemically, gingerol is a relative of capsaicin, the compound that gives chile peppers their spiciness. It is normally found as a pungent yellow oil, but also can form a low-melting crystalline solid.
Cooking ginger transforms gingerol into zingerone, which is less pungent and has a spicy-sweet aroma.
Physiological effects
Gingerol may reduce nausea caused by motion sickness or pregnancy[1] and may also relieve migraine.[2]
[6]-Gingerol has been used to induce a suspended animation-like hypothermic state in rats [3].
Gingerol seems to be effective in an animal model of rheumatoid arthritis.[4]
Ginger or gingerol have been evaluated in a large number of clinical studies.[5]
References
- ↑ Ernst, E; Pittler (2000). "Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials". British journal of anaesthesia. 84 (3): 367–71. PMID 10793599. More than one of
|author2=and|last2=specified (help) - ↑ Mustafa, T; Srivastava (1990). "Ginger (Zingiber officinale) in migraine headache". Journal of ethnopharmacology. 29 (3): 267–73. doi:10.1016/0378-8741(90)90037-T. PMID 2214812. More than one of
|author2=and|last2=specified (help) - ↑ Ueki, S.; Miyoshi, M.; Shido, O.; Hasegawa, J.; Watanabe, T. (2008). "Systemic administration of 6-gingerol, a pungent constituent of ginger, induces hypothermia in rats via an inhibitory effect on metabolic rate". European journal of pharmacology. 584 (1): 87–92. doi:10.1016/j.ejphar.2008.01.031. PMID 18295202. More than one of
|author2=and|last2=specified (help); More than one of|author3=and|last3=specified (help); More than one of|author4=and|last4=specified (help); More than one of|author5=and|last5=specified (help) - ↑ "Comparative effects of two gingerol-containing Zingiber officinale extracts on experimental rheumatoid arthritis".
- ↑ "Ginger Clinical Studies".
