Hepatosplenomegaly

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Hepatosplenomegaly
Classification and external resources
ICD-10	R 16.2
ICD-9	571.8 Image =
MedlinePlus	003275

Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly). Hepatosplenomegaly can occur as the result of acute viral hepatitis or infectious mononucleosis, or it can be the sign of a serious and life threatening lysosomal storage disease.

Contents

1 Common causes
2 Rare disorders
3 References
4 External links

Common causes

Infection:
- Acute viral hepatitis^[1]^[2]
- Infectious mononucleosis^[2]^[1]
- Cytomegalovirus^[2]^[1]
- Rubella^[1]
- Malaria^[1]
- Leishmaniasis^[1]
Haematological disease:

Metabolic disease:
- Niemann Pick disease

Chronic liver disease and portal hypertension:
- Chronic active hepatitis^[2]

Amyloidosis^[2]

Acromegaly^[2]

Systemic lupus erythematosus^[2]

Rare disorders

Multiple sulfatase deficiency

References

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External links

National Niemann Pick Disease Foundation
Hide and Seek Foundation For Lysosomal Disease Research
1516961800 at GPnotebook
vii/h/HEPATOSPLENOMEGALY article at GE's Medcyclopaedia

This medical sign article is a stub. You can help ssf by expanding it.

Symptoms and signs: digestive system and abdomen (R10-R19, 787,789)

Upper GI tract	Nausea/Vomiting · Heartburn · Dysphagia (Oropharyngeal, Esophageal) Halitosis
Lower GI tract	gas: Flatulence · Abdominal distension · Bloating · Belching · Tympanites stool: Fecal incontinence (Encopresis) · Rectal tenesmus blood: Fecal occult blood Diarrhea Football sign

Hepatosplenomegaly/Hepatomegaly
Jaundice

Abdominopelvic cavity

Abdominal – general

Abdominal pain (Acute abdomen, Colic, Baby colic)

Abdominal guarding · Abdominal mass

Shifting dullness · Bulging flanks · Puddle sign

anat(t, g, p)/phys/devp/cell

noco/cong/tumr, sysi/epon

proc, drug(A2A/2B/3/4/5/6/7/14/16)

cs:Hepatosplenomegalie de:Hepatosplenomegalie es:Hepatosplenomegalia fa:بزرگی طحال و کبد fr:Hépatosplénomégalie id:Hepatosplenomegali pl:Hepatosplenomegalia pt:Hepatoesplenomegalia fi:Hepatosplenomegalia

sv:Hepatosplenomegali

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 medcyclopaedia: Hepatosplenomegaly Retrieved on Nov 23, 2009
↑ ^2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 GPNotebook: hepatosplenomegaly Retrieved on Nov 23, 2009

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