Injection fraction
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Injection fraction, IF=EDV/ESV, is the inverse operation of the myocardial ejection fraction. "Ejection Fraction" is historically and mathematically derived from Cardiac Output first posited by Adolph Fick 1829-1901. Ejection fraction (EF) is most readily appreciated as the difference between end systolic volume and end diastolic volume. Mathematical derivation as stroke volume and minimum volume or MinV similarly apply as determinants of Systole.
Ejection Fraction is noninvasively and inexpensively reproduced echocardiographically in many languages as EF=ESV/EDV.
Determinants of Diastole implies an inverse mathematical approach to the work of Fick. Injection fraction as a determinant of diastole is the difference between end diastolic volume and end systolic volume. IF=EDV/ESV. Decline of injection fraction further implies a measurable determinant of diastolic heart failure.
Decline of injection fraction will likely closely follow clinically relevant time ratios such as E:A intervals across the mitral valve.
It can be measured with a MUGA scan.[1]
References
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