Lattice corneal dystrophy type I

Lattice corneal dystrophy type I
Classification and external resources
File:Lattice corneal dystrophy type 1.JPEG A network of thick linear corneal opacities in patient with a variant of LCD1 (LCD type III) due to a homozygous p. Leu527Arg mutation in the TGFBI gene
OMIM	122200
eMedicine	article/1193793

Lattice corneal dystrophy type I (LCD1; Biber-Haab-Dimmer dystrophy) is a rare form of human corneal dystrophy. It is caused by mutations in TGFBI gene encoding keratoepithelin. It has no systemic manifestations, unlike the other type of the dystrophy, LCDII. Filamentous opacities appear in the cornea with intertwining delicate branching processes. The disease is bilateral, usually noted before the end of the first decade of life.

LCDI was first described by Swiss ophthalmologist Hugo Biber in 1890.

References

ru:Решётчатая дистрофия роговицы, тип I