Linsidomine

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Linsidomine
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Systematic (IUPAC) name
5-imino-3-morpholin-4-yl-5H-1,2,3-oxadiazol-3-ium-2-ide
Identifiers
ATC code C01DX18 (WHO)
PubChem CID 5219
Chemical data
Formula C6H10N4O2
Molar mass 170.17 g/mol[[Script error: No such module "String".]]
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Linsidomine is a vasodilator. Linsidomine (SIN-1) is a metabolite of the antianginal drug molsidomine and acts by releasing NO from the endothelial cells nonenzymatically. It also hyperpolarizes the cell membrane through influencing the sodium-potassium pump and thereby rendering it less responsive to adrenergic stimulation ). Linsidomine injection at a dose of 1 mg produces usable erection in about 70% of patients and full erection in up to 50% of patients . Linsidomine does not appear to be associated with priapism .