Methscopolamine

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Methscopolamine
File:Methscopolamine.png
Systematic (IUPAC) name
(1R,2S,4R,5S,7R)-{[(2R)-3-hydroxy-2-phenylpropanoyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane
Identifiers
CAS Number 155-41-9
ATC code none
PubChem CID 441342
DrugBank APRD00314
Chemical data
Formula C18H24NO4
Molar mass 318.388 g/mol[[Script error: No such module "String".]]
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Methscopolamine, usually provided as a bromide salt (Pamine), is an oral medication used along with other medications to treat peptic ulcers by reducing stomach acid secretion. With the advent of proton pump inhibitors and antihistamine medications it is rarely used for this anymore. It can also be used for stomach or intestinal spasms, to reduce salivation, and to treat motion sickness. Methscopolamine is also commonly used as a drying agent, to dry up post-nasal drip, in cold and allergy medications (Extendryl, AlleRx, Rescon).

Methscopolamine, a methylated derivative of scopolamine, is a muscarinic antagonist structurally similar to the neurotransmitter acetylcholine. Its mechanism of action involves blocking the muscarinic acetylcholine receptors.