Myositis ossificans
This article appears to contradict the article fibrodysplasia ossificans progressiva. Please see discussion on the linked talk page. Please do not remove this message until the contradictions are resolved. (June 2006) |
This article's factual accuracy is disputed. (April 2008) |
Myositis ossificans | |
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Classification and external resources | |
ICD-10 | M61. |
ICD-9 | 728.1 |
MeSH | D009221 |
Myositis ossificans comprises two syndromes characterized by heterotopic ossification (calcification) of muscle.
Classification
- In the first, and by far most common type, nonhereditary myositis ossificans (commonly referred to simply as "myositis ossificans", as in the remainder of this article), calcifications occur at the site of injured muscle, most commonly in the arms or in the quadriceps of the thighs.
- The second condition, myositis ossificans progressiva (also referred to as fibrodysplasia ossificans progressiva) is an inherited affliction, autosomal dominant pattern, in which the ossification can occur without injury, and typically grows in a predictable pattern.
Presentation
The condition may sometimes be diagnosed from radiographs obtained for unrelated problems.
Most (i.e. 80%) ossifications arise in the thigh or arm, and are caused by a premature return to activity after an injury. Other sites include intercostal spaces, erector spinae, pectoralis muscles, glutei, and the chest. Hazy densities are sometimes noted approximately one month after injury, while the denser opacities eventually seen may not be apparent until two months have passed.
If the calcification is located in the adductor muscles, it is known as "Prussian's disease".
Treatment
Treatment is initially conservative, as some patients' calcifications will spontaneously be reabsorbed, and others will have minimal symptoms. In occasional cases, surgical debridement of the abnormal tissue is required, although success of such therapy is limited.
References
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