Oxycodone/naloxone
From Self-sufficiency
| File:Oxycodone.svg | |
| File:Naloxone.svg | |
| Combination of | |
|---|---|
| Oxycodone | Opioid analgesic |
| Naloxone | Opioid receptor antagonist |
| Clinical data | |
| Routes of administration | Oral |
The combination oxycodone/naloxone is available as prolonged-release tablets under the trade name Targin (produced by Mundipharma). It "significantly improv[ed] opioid-induced constipation" in a 2008 study.[1] It was released in 2006 in Germany and will be available in some other European countries beginning in 2009.[2]
References
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- ↑ Simpson K; et al. (2008 Dec). "Fixed-ratio combination oxycodone/naloxone compared with oxycodone alone for the relief of opioid-induced constipation in moderate-to-severe noncancer pain". Curr Med Res Opin. 24 (12): 3503–3512. doi:10.1185/03007990802584454. PMID 19032132. Retrieved 2009-04-09. Check date values in:
|date=(help) - ↑ Mundipharma (2009-01-26). "Targin (oral oxycodone/naloxone prolonged-release tablet) now launching across Europe to control severe chronic pain with significantly reduced risk of opioid-induced constipation". Retrieved 2009-04-09.
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