Piperonyl butoxide

Piperonyl butoxide
Piperonyl butoxide
IUPAC name 5-[2-(2-butoxyethoxy)ethoxymethyl] -6-propyl-1,3-benzodioxole
style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers
CAS number	51-03-6 Y
SMILES
style="background: #F8EABA; text-align: center;" colspan="2" | Properties
Molecular formula	C19H30O5
Molar mass	338.438 g/mol
Density	1.05 g/cm3
Boiling point	155 °C
style="background: #F8EABA; text-align: center;" colspan="2" | Hazards
Flash point	170 °C
Y (what is this?)  (verify) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Piperonyl butoxide (PBO) is a pesticide synergist. It does not, by itself have pesticidal properties. However, when added to insecticide mixtures, typically pyrethrin, pyrethroid, and carbamate insecticides, their potency is increased considerably.

Piperonyl butoxide is a potent cytochrome P450 and non-specific esterase inhibitor. These enzyme families act as the principal detoxification pathways for many pests, and so inhibiting them allows higher unmetabolised systemic concentrations of the active insecticide to remain within the target animal for a longer period.

Piperonyl butoxide is moderately stable, and is a semisynthetic derivative of safrole.

It is debatable whether the substance is oncogenic, mutagenic, or teratogenic in humans. Its acute oral and dermal toxicity in mammals is low

References

Moores, G. D., Philippou, D., Borzatta, V., Trincia, P., Jewess, P., Gunning, R., Bingham, G. An analogue of piperonyl butoxide facilitates the characterisation of metabolic resistance. Pest Manag. Sci. 65: 150-154 (2009).cs:Piperonylbutoxid de:Piperonylbutoxid es:Butóxido de piperonilo nl:Piperonylbutoxide