Quassin
From Self-sufficiency
| Quassin | |
|---|---|
| (+)-Quassin | |
| 2,12-dimethoxypicrasa-2,12-diene-1,11,16-trione | |
| Other names (3aS,6aR,7aS,8S,11aS,11bS,11cS) -1,3a,4,5,6a,7,7a,8,11,11a,11b,11c-dodecahydro-2,10-dimethoxy-3,8,11a,11c- tetramethyldibenzo[de,g]chromene-1,5,11-trione | |
| style="background: #F8EABA; text-align: center;" colspan="2" | Identifiers | |
| CAS number | 76-78-8 |
| PubChem | 10971 |
| EC number | 200-985-9 |
| SMILES | Script error: No such module "collapsible list". |
| InChI key | IOSXSVZRTUWBHC-LBTVDEKVBB |
| style="background: #F8EABA; text-align: center;" colspan="2" | Properties | |
| Molecular formula | C22H28O6 |
| Molar mass | 388.45 g mol−1 |
| Appearance | White crystalline substance |
| Melting point |
200-222 °C |
| Boiling point |
586 °C |
| Solubility in water | Insoluble |
| Vapor pressure | 13 mmHg (@25 °C) |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) | |
| Infobox references | |
Quassin is a white bitter, crystalline substance extracted from the quassia tree. It is the bitterest substance found in nature with a bitter threshold of 0.08 ppm and it is 50 times more bitter than quinine.[1]
Quassin is used as a medicine in traditional Chinese medicine.
Extracts of the Bitter tree (or bitter wood) (Quassia amara L. or Picrasma excelsa) are also used as additives in soft drinks.[1]
Although its skeleton possesses 20 carbon atoms, quassin is not a diterpene but rather a triterpene lactone, which derives from euphol by loss of 10 carbon atoms including C4.
References
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<references />, or <references group="..." />- ↑ 1.0 1.1 Scientific Committee on Food Opinion of the Scientific Committee on Food on quassin (expressed on 2 July 2002). SCF/CS/FLAV/FLAVOUR/29 Final
