Ruboxistaurin
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| File:Ruboxistaurin.png | |
| Systematic (IUPAC) name | |
|---|---|
|
(9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-di(metheno)dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20-dione | |
| Identifiers | |
| CAS Number | 169939-94-0 |
| ATC code | none |
| PubChem | CID 153999 |
| Chemical data | |
| Formula | C28H28N4O3 |
| Molar mass | 468.546 g/mol[[Script error: No such module "String".]] |
Ruboxistaurin (proposed brand name Arxxant) is an investigational drug for diabetic peripheral retinopathy. It is currently being investigated by Eli Lilly and Company.
On February, 2006, Lilly submitted a New Drug Application for ruboxistaurin, and on August 18, 2006, Lilly received an "approvable" letter from the United States Food and Drug Administration for ruboxistaurin,[1] with a request for an additional clinical trial, which would take 5 years to complete.[2]
Mechanism of action
Ruboxistaurin is an inhibitor of protein kinase C-beta.[3]
References
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This pharmacology-related article is a stub. You can help ssf by expanding it. |
- ↑ "Drugs.com, Eli Lilly and Company Announces Approvable Letter Issued by FDA for Arxxant". Retrieved 2008-02-15.
- ↑ "Drugs.com, Lilly Announces FDA Requirement of Additional Clinical Trial Before Ruboxistaurin Could Be Approved for Treatment of Diabetic Retinopathy". Retrieved 2008-02-15.
- ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
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