Sivelestat
From Self-sufficiency
File:Sivelestat.png | |
Systematic (IUPAC) name | |
---|---|
N-{2-[({4-[(2,2-dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine | |
Clinical data | |
Routes of administration | IV |
Legal status | |
Legal status |
|
Identifiers | |
CAS Number | 127373-66-4 |
ATC code | none |
PubChem | CID 107706 |
Chemical data | |
Formula | C20H22N2O7S |
Molar mass | 434.46 g/mol[[Script error: No such module "String".]] |
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Sivelestat (INN, research name ONO 5046, marketed as Elaspol) is an inhibitor of human neutrophil elastase.[1]
It is commonly used in the treatment of acute respiratory failure.[2]
Synthesis
K. Imaki, Y. Arai, T. Okegawa, U.S. Patent 5,017,610 (1991).
References
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