Sivelestat

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Sivelestat
File:Sivelestat.png
Systematic (IUPAC) name
N-{2-[({4-[(2,2-dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine
Clinical data
Routes of
administration
IV
Legal status
Legal status
  • ℞ (Prescription only)
Identifiers
CAS Number 127373-66-4
ATC code none
PubChem CID 107706
Chemical data
Formula C20H22N2O7S
Molar mass 434.46 g/mol[[Script error: No such module "String".]]
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Sivelestat (INN, research name ONO 5046, marketed as Elaspol) is an inhibitor of human neutrophil elastase.[1]

It is commonly used in the treatment of acute respiratory failure.[2]

Synthesis

490px

K. Imaki, Y. Arai, T. Okegawa, U.S. Patent 5,017,610 (1991).

References

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