Search results

...ariety of effects. It is a [[competitive antagonist]] for the [[muscarinic acetylcholine receptor]]. It is classified as an [[anticholinergic drug]]. Being potenti ...AV) of the [[heart]], opposes the actions of the [[vagus nerve]], blocks [[acetylcholine]] [[receptor (biochemistry)|receptor]] sites, and decreases [[bronchial]] [

..., Aoki K, Takagi M, Miyatake M, Suzuki T |title=A putative sigma1 receptor antagonist NE-100 attenuates the discriminative stimulus effects of ketamine in rats | ...ranados et al |title= A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression|journal=Archives of General Psych

...Maass A, Mohr K | title = Opposite effects of alcuronium on agonist and on antagonist binding to muscarinic receptors. | journal = Eur J Pharmacol | volume = 305

...ceptor|NMDA]] and [[CHRNB2|β₂-subunit]]-containing [[nicotinic acetylcholine receptor|nACh channel]]s, weakly inhibits [[AMPA receptor|AMPA]], [[kainate ...versed by [[GABAA receptor|benzodiazepine receptor]] [[receptor antagonist|antagonist]]s. Mirroring this, animals which have developed tolerance to the anxiolyti

...at= |work=}}</ref> It has been hypothesized that CBD acts as an allosteric antagonist at the CB₁ receptor and thus alters the psychoactive effects of ...ly potent alpha(2)-adrenoceptor agonist and moderately potent 5HT receptor antagonist | journal = British Journal of Pharmacology | volume = 159| issue = 1| page

...ub>]] neuronal [[nicotinic acetylcholine receptor]] [[nicotinic antagonist|antagonist]] in rat receptors, expressed in human embryonic kidney cell lines.<ref nam ...half life, it is more difficult to titrate. If too large a dose of opioid antagonist is given to a dependent patient, it will result in withdrawal symptoms (pos

...of [[dissociative anesthetic]]s. PCP works primarily as an [[NMDA receptor antagonist]], which blocks the activity of the [[NMDA receptor]] and, like most antigl In a similar manner, PCP and analogues also inhibit [[nicotinic acetylcholine receptor]] channels (nAChR). Some analogues have greater potency at nAChR t

...fects of salvinorin A in mice are blocked by κ-Opioid receptor [[receptor antagonist|antagonists]].<ref name="Zhang2005pabs">[[#refZhang2005|Zhang et al. 2005]] ...fy electrically-induced contractions, but ''not'' those of [[exogenous]] [[acetylcholine]]<ref>.[[#refCapasso2006|Capasso 2006]].</ref> Results from a small study b

...e]] [[hallucinogen]]. Its [[mechanism of action]] is as an [[NMDA receptor antagonist]], producing effects similar to those of the controlled substances [[ketam ...ibition|Uncompetitive]] [[NMDA receptor]] (PCP site) [[receptor antagonist|antagonist]] (K_i = 7,253 nM).<ref name="pmid10064839">{{cite journal | auth

...and can be prevented by prior administration of pirenzepine, a muscarinic acetylcholine receptor blocking agent.<ref>{{cite journal |title=Muscarinic cholinergic m ...5 | title = Resuscitative Effect of a &gamma;-Aminobutyric Acid B Receptor Antagonist on &gamma;-Hydroxybutyric Acid Mortality in Mice | journal = Annals of Emer