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...ount for much of its anti-malarial activity; the drug concentrates in the acidic food vacuole of the parasite and interferes with essential processes. ...larial [[parasite]] must degrade [[hemoglobin]] to acquire essential amino acids, which the parasite requires to construct its own protein and for energy me

A dose of 500 milligrams of SAMe (S-adenosyl-methionine,is an amino acid naturally formed in the body) given together with a large dose of aspi ...er oral administration. Acetylsalicylic acid is poorly soluble in the [[pH|acidic]] conditions of the stomach, which can delay absorption of high doses for 8

...egments. Many proteins are polyampholytes, as some amino acids tend to be acidic while others are basic.

...ogenous Reactions Important | pages = 15–16}}</ref> Powdered iron in an acidic solvent was used in the [[Bechamp reduction]] the reduction of [[nitrobenz ...ten the amino acid chosen for this purpose is the cheapest and most common amino acid, [[glycine]], leading to "iron glycinate" supplements.<ref name="Ashme

..., with its structure being determined later, in 1911.<ref name=Mann/> This amino acid has [[antioxidant]] properties, but its chemistry differs from convent ...ine can be slowly oxidized over several days to the [[disulphide]] form in acidic solutions.<ref>{{cite journal |author=Heath H, Toennies G |title=The prepar

...present value, and discovered the ability of ethylene oxide to react with acids and salts of metals.<ref name="oe1">{{cite book ...a the [[Nucleophilic substitution|'''S_N2''']] mechanism both in acidic (weak nucleophiles: water, alcohols) and alkaline media (strong nucleophile

...form multiple [[chelate]] rings. This property makes polyamino carboxylic acids useful in a wide variety of chemical, medical and environmental application ...is [[glycine]], H₂NCH₂CO₂H, in which the amino group, NH₂,is separated from the carboxyl group, COOH by a singl

Porphyrins are the conjugate acids of [[ligand]]s that bind [[metals]] to form [[complex (chemistry)|complexes ...minolevulinic acid|D-aminolevulinic acid]] (dALA) by the reaction of the [[amino acid]] [[glycine]] with [[succinyl-CoA]] from the [[citric acid cycle]]. T

...hat catalyze the hydrolysis of terminal peptide bonds, liberating one free amino acid at a time. ...k is the hydrolysis of [[peptide bond|peptides]] to smaller fragments or [[amino acid]]s.

...rotein]]s. These calculations complement the pKa values reported for amino acids in their free state, and are used frequently within the fields of [[molecul ==Amino acid pKa values==

...issociated acid becomes undetectable. p''K''_a values for strong acids can, however, be estimated by theoretical means or by extrapolating from me ...a prerequisite for a quantitative understanding of the interaction between acids or bases and metal ions to form [[Stability constants of complexes|complexe

...ties and function. This is true of hemoglobin, where the sequence of amino acids may affect crucial functions such as the protein's affinity for oxygen. ...nces in humans and chimpanzees are nearly identical, differing by only one amino acid in both the alpha and the beta globin protein chains. These difference

...phosphorylation is catalyzed by [[phosphatase]]s. Phosphorylation of any [[amino acid]] having a free [[hydroxyl group]] on a given protein can change the f {{Seealso|Phosphoric acids and phosphates}}

...protease derivatives are involved in the apoptotic pathway induced by the acidic environment triggered by glutamate. These cysteine proteases include calpa ...JNJ460. A peptide mixture was made by washing off unbound portions of the amino acid sequence in a reverse column. The resulting mixture was then suspende

...cule whose [[proteolysis]] generates [[beta amyloid]] (Aβ), a 39- to 42-[[amino acid]] [[peptide]] whose [[amyloid]] fibrillar form is the primary componen ...APP have been observed in humans, ranging in length from 365 to 770 amino acids, with certain isoforms preferentially expressed in neurons; changes in the

Most nonsteroidal anti-inflammatory drugs are weak acids, with a pKa of 3-5. They are absorbed well from the [[stomach]] and intesti ...gastrointestinal tract]] (GIT). NSAIDs cause a dual insult on the GIT: the acidic molecules directly irritate the gastric [[mucosa]], and inhibition of COX-1

...nto a strong and rubbery [[gel]] compared to the fragile curds produced by acidic coagulation alone. It also allows curdling at a lower acidity—important b ...kdown of casein proteins and [[butterfat|milkfat]] into a complex mix of [[amino acid]]s, [[amine]]s, and [[fatty acid]]s.