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  • * Chloroquine is in clinical trials as an investigational [[antiretroviral]] in humans with [[AIDS|HIV-1/AIDS]] and as a potential [[Antiviral drug|an ...smodium ovale|ovale]]'' and ''[[Plasmodium malariae|malariae]]''. Popular drugs based on chloroquine phosphate (also called nivaquine) are '''Chloroquine F
    16 KB (2,187 words) - 16:41, 27 September 2010
  • ...the primary reason that it is used in tandem with the three aforementioned drugs, particularly isoniazid.<ref name="Erlich">Erlich, Henry, W Ford Doolittle, ...can cause a range of adverse reactions when taken concurrently with other drugs.<ref name="Collins">Collins, R Douglas. Atlas of Drug Reactions. New York,
    18 KB (2,471 words) - 16:43, 27 September 2010
  • ...nistration]] (FDA) on December 18, 1998 and is thus the fifteenth approved antiretroviral drug in the United States. Its patent expired in the United States on 2009 Abacavir tablets and oral solution, in combination with other antiretroviral agents, are indicated for the treatment of HIV-1 infection.
    8 KB (1,124 words) - 16:44, 27 September 2010
  • ...nation with other [[antiretroviral drug]] therapy as part of highly active antiretroviral therapy (HAART). ...n has also been recorded with [[allopurinol]], and administration of these drugs together should be avoided.<ref name="Videxpi" />
    9 KB (1,239 words) - 16:44, 27 September 2010
  • ...dine]] (AZT) and again in 2002 as a once-a-day dosed medication. The fifth antiretroviral drug on the market, it was the last NRTI for three years while the approval * Lamivir 150 for treatment of HIV along with 2 other drugs . Cipla Ltd - India
    9 KB (1,248 words) - 16:44, 27 September 2010
  • ...as an extended-release version for once-a-day dosing in 2001. The fourth [[antiretroviral drug]] on the market, its patent expired in the United States on 2008-06-25 ...nhibit the intracellular [[phosphorylation]] of stavudine. Other anti-HIV drugs do not possess this property.
    4 KB (574 words) - 16:44, 27 September 2010
  • ...lead Sciences]] under the trade name '''Viread''', belongs to a class of [[antiretroviral drug]]s known as nucleotide analogue [[reverse transcriptase inhibitor]]s ( Tenofovir is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults. This indication is b
    6 KB (871 words) - 16:45, 27 September 2010
  • ...bitor]] (NNRTI) and is used as part of highly active [[Antiretroviral drug|antiretroviral therapy]] (HAART) for the treatment of a human immunodeficiency virus ([[HI Antiretroviral Guidelines currently recommends the use of efavirenz in combination with [[
    10 KB (1,441 words) - 16:45, 27 September 2010
  • As with other [[antiretroviral drug]]s, HIV rapidly develops resistance if nevirapine is used alone, so re ...ad]] effectively when used as initial antiretroviral therapy (''i.e.'', in antiretroviral-naive patients).<ref name=INCAS_1998/> Some clinical trials have demonstrat
    15 KB (2,090 words) - 16:45, 27 September 2010
  • ...ase inhibitor]] used as a component of [[antiretroviral drug|highly active antiretroviral therapy]] (HAART) to treat [[HIV]] infection and [[AIDS]]. ...and raised the bar on design and introduction of subsequent antiretroviral drugs. Protease inhibitors changed the very nature of the AIDS epidemic from one
    3 KB (320 words) - 15:07, 6 July 2010
  • ...low-income countries), both of which represent a [[Fixed dose combination (antiretroviral)|co-formulation]] with a sub-therapeutic dose of [[ritonavir]], as a compon ...man Services|DHHS]].<ref name="dhhs">DHHS panel. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents (May 4, 2006). (Available f
    8 KB (1,109 words) - 16:45, 27 September 2010
  • ...onavir''', with trade name '''Norvir''' ([[Abbott Laboratories]]), is an [[antiretroviral drug]] from the [[protease inhibitor (pharmacology)|protease inhibitor]] cl ...ors. This inhibition leads to higher plasma concentrations of these latter drugs, allowing the clinician to lower their dose and frequency and improving the
    9 KB (1,233 words) - 15:07, 6 July 2010
  • ...sing schedules, and therefore has the potential to increase adherence to [[antiretroviral]] therapy. ...tween two U.S. pharmaceutical companies to combine their patented anti-HIV drugs into one product.<ref>{{cite web | author= | title=Search for Tradename: At
    6 KB (773 words) - 16:45, 27 September 2010
  • ...in reducing [[Polypharmacy|pill burden]] and in aiding compliance with the antiretroviral drug therapy. ...Administration]] on September 26, 1997, making it the thirteenth approved antiretroviral. It is marketed by [[GlaxoSmithKline]].
    3 KB (364 words) - 15:07, 6 July 2010
  • ...like other PIs is generally used in combination with other antiretroviral drugs. ...d it for therapeutic use on March 14, 1997, making it the twelfth approved antiretroviral. The initial product launched proved to be the largest "biotech launch" in
    8 KB (1,160 words) - 16:45, 27 September 2010
  • ...e tablet, it reduces the [[pill burden]] and increases [[compliance]] with antiretroviral therapy. The drug has also found some potential as a preventative measure i ...bstract/2009/69070/Emtricitabine_Tenofovir_Disoproxil_Fumarate__In.5.aspx].Drugs 2009;69(7):843-857.doi: 10.2165/00003495-200969070-00005.</ref>
    3 KB (396 words) - 15:07, 6 July 2010
  • Related drugs include the sodium salts [[sodium valproate]], used as an anticonvulsant, a ...perties of valproate: a summary after 35 years of clinical experience. CNS Drugs 2002; 16:695–714.</ref> Valproic acid has also been used for migraine pro
    25 KB (3,328 words) - 16:47, 27 September 2010
  • ...or|nucleoside analog reverse transcriptase inhibitor]] (NRTI), a type of [[antiretroviral drug]] used for the treatment of HIV/AIDS. It is an [[analog (chemistry)|an ...Health Organization]]'s "[[WHO Model List of Essential Medicines|Essential Drugs List]]", which is a list of minimum medical needs for a basic health care s
    21 KB (3,049 words) - 16:51, 27 September 2010