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...reases firing of the [[sinoatrial node]] (SA) and conduction through the [[atrioventricular node]] (AV) of the [[heart]], opposes the actions of the [[vagus nerve]], b ...k|third-degree heart block]] with a high [[Purkinje fibers|Purkinje]] or [[Atrioventricular node|AV-nodal]] [[escape rhythm]]. It is usually not effective in [[Second

...ted manner in response to a complex endogenous [[Autonomic]] physiologic [[excitation-contraction coupling|electrical stimulus]], as a result, positive fluid pre ...al systole. The aortic valve and pulmonary valve remain closed, while the atrioventricular mitral and tricuspid valves remain open because the pressure gradient betwe