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Administration to opioid-dependent individuals may cause symptoms of [[opioid withdrawal]], including restlessness, agitation, nausea, vomiting, a [[tachycardia|fas ...hine equivalence/day), is prescribed any dose of opioid accompanied by a [[benzodiazepine]], or is suspected or known to use opioids nonmedically.<ref>{{cite journal

...] properties but, as with other barbiturates, has been superseded by the [[benzodiazepine]]s for these indications. The [[World Health Organization]] recommends its ...ed a commonly prescribed sedative and hypnotic until the introduction of [[benzodiazepine]]s in the 1950s.<ref name="Sneader2005">{{cite book

...adaras R, Ivaskevicius J |title=Effects of ketamine on precipitated opiate withdrawal |journal=Medicina |volume=42 |issue=8 |pages=625–34 |year=2006 |pmid=1696 ...drug|psychotropic]] side effects are less apparent and well managed with [[benzodiazepine]]s.<ref name="elia">{{Cite journal|author=Elia N, Tramèr MR |title=Ketamin

...2244768|pmid = 7862891}}</ref> Indeed, in humans given 30% N₂O, benzodiazepine receptor antagonists reduced the subjective reports of feeling "high", but ...opioid action of psychotropic analgesic nitrous oxide in alcohol and drug withdrawal|journal = Clinical Neuropharmacology|volume = 19|issue = 3|pages = 246–51

...cohol]] (ethanol), [[gamma-Hydroxybutyrate]] (G, GHB), [[barbiturate]]s, [[benzodiazepine]]s, and [[nonbenzodiazepine]]s ===Withdrawal===

...iazepam enhances the effect of the neurotransmitter GABA by binding to the benzodiazepine site on the [[GABAA receptor|GABA_A receptor]] leading to [[centr ...e|tolerance]], [[benzodiazepine dependence]] as well as a [[benzodiazepine withdrawal syndrome]] upon dose reduction; additionally after cessation of benzodiazep

...''', [[#Availability|among others]]) is an intermediate-acting 3-hydroxy [[benzodiazepine]]. It is generally prescribed for the short-term treatment of [[Insomnia|sl * [[Hypersensitivity]] or allergy to any drug in the [[benzodiazepine]] class

...lePath=journals/ijpharm/vol4n2/gaba.xml Gabapentin-Assisted Benzodiazepine Withdrawal In A Multidrug Dependent Patient]</ref> ...wal,<ref>{{cite journal|title=Add-on gabapentin in the treatment of opiate withdrawal|journal=Progress in Neuro-Psychopharmacology and Biological Psychiatry|year

...=317–9 | pmid =12022028 | doi =10.1055/s-2002-30650 }}</ref> Post acute withdrawal syndrome affects many aspects of [[recovery]] and everyday life, including ...use. [[Benzodiazepines]] are the most notable drug for inducing prolonged withdrawal effects with symptoms sometimes persisting for years after cessation of use

...est that buprenorphine and naloxone at a 4:1 ratio will produce unpleasant withdrawal symptoms if taken intravenously by patients who are addicted to opioids,<re ...if increased doses of buprenorphine are administered. This form of intense withdrawal may last anywhere from two to approximately thirty-six hours. This does no

...er kilogram per day, in 3 or more divided doses), both for acute [[alcohol withdrawal]] and medium- to long-term detoxification.<ref>An author/scientist Gian Lui ...olloquially as "[[Rohypnol]]", the trade name of a certain potent hypnotic benzodiazepine, [[flunitrazepam]]. It has a [[salt]]y taste, but as it is colourless and o