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  • ...) were removed from major pharmaceutical markets in the mid-2000s due to [[COX-2 inhibitor#Risks and adverse effects|vascular safety concerns]]. In additio
    3 KB (414 words) - 22:17, 21 September 2010
  • ...ture of [[celecoxib]], [[rofecoxib]] and other members of this drug class. COX-2 selectivity does not seem to reduce other [[adverse drug reaction|adverse e The COX-2 gene was discovered by UCLA scientist Dr. Harvey Herschman. [http://faculty
    30 KB (4,194 words) - 22:17, 21 September 2010

Page text matches

  • 54 KB (8,488 words) - 21:31, 2 July 2010
  • -Inhibition of gene transcription for COX-2, cytokines, cell adhesion molecules and inducible NO synthetase
    7 KB (872 words) - 16:41, 27 September 2010
  • 12 KB (1,557 words) - 16:44, 27 September 2010
  • ...nocarcinomas may be explained by its inhibition of [[Cyclooxygenase|PTGS2 (COX-2)]] enzymes expressed in them.<ref>{{Cite journal|author=Wolff, ''et al.''|t ===PTGS1 [COX-1] and PTGS2 [COX-2] inhibition===
    78 KB (10,918 words) - 16:52, 27 September 2010
  • ...and bleeding, selective [[COX-2 inhibitor]]s were developed to inhibit the COX-2 isoform without inhibition of COX-1.<ref name=emedicinepainmeds>{{Cite web|
    29 KB (3,955 words) - 22:17, 21 September 2010
  • 22 KB (2,916 words) - 16:50, 27 September 2010
  • 69 KB (10,077 words) - 21:35, 20 September 2010
  • ...ase]] (COX), and recent findings suggest that it is highly selective for [[COX-2]].<ref name="Hinz_2008">{{Cite pmid|17884974}}</ref> While it has [[analges Because of its selectivity for COX-2 it does not significantly inhibit the production of the pro-clotting [[thro
    54 KB (7,376 words) - 16:52, 27 September 2010
  • 17 KB (2,020 words) - 12:26, 7 July 2010
  • 1 KB (177 words) - 12:27, 7 July 2010
  • 1 KB (130 words) - 13:31, 19 September 2010
  • 1 KB (203 words) - 13:31, 19 September 2010
  • 61 KB (8,890 words) - 13:32, 19 September 2010
  • 12 KB (1,699 words) - 10:09, 20 September 2010
  • ...spholipase|phospholipase A2]] (PLA2), [[cyclooxygenase|cyclooxygenase-2]] (COX-2), and [[prostaglandin E2 synthase]]. These enzymes ultimately mediate the s
    27 KB (3,703 words) - 20:20, 20 September 2010
  • 33 KB (4,747 words) - 21:32, 20 September 2010
  • The effect of [[COX-2 selective inhibitor|COX-2 inhibitors]] such as [[rofecoxib]] and [[celecoxib]] upon the risk of colon
    94 KB (13,321 words) - 21:32, 20 September 2010
  • 22 KB (3,222 words) - 21:33, 20 September 2010
  • 4 KB (508 words) - 21:36, 20 September 2010
  • 45 KB (6,263 words) - 21:37, 20 September 2010

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