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...on the distal tubules is independent of any inhibitory effect on carbonic anhydrase or aldosterone; it also abolishes the corticomedullary osmotic gradient and ...t limited by development of acidosis, as it is with the carbonic anhydrase inhibitors.

'''Acetazolamide''', sold under the trade name '''Diamox''', is a [[carbonic anhydrase inhibitor]] that is used to treat [[glaucoma]], [[epileptic seizure]]s, [[b Acetazolamide is a [[carbonic anhydrase inhibitor]], which means that it forces the kidneys to excrete bicarbonate

...nner, hemoglobin ligands also include [[competitive inhibition|competitive inhibitors]] such as [[carbon monoxide]] (CO) and [[allosteric regulation|allosteric]] ...enzyme [[carbonic anhydrase]], carbon dioxide reacts with water to give [[carbonic acid]], which decomposes into [[bicarbonate]] and [[proton]]s: