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• Quinine
  ...economically practical source of quinine. However, under wartime pressure, research towards its synthetic production was undertaken. A formal chemical synthesi ...r the early treatment of moderately severe malaria in children: randomised clinical trial | journal=Brit Med J | volume=332 | issue=7549 | pages=1055–57
  27 KB (3,844 words) - 16:41, 27 September 2010
• Mefloquine
  ...floquine was developed in the 1970s at the [[Walter Reed Army Institute of Research]] in the U.S. as a synthetic analogue of [[quinine]]. ...[[Hoffman-LaRoche]], a Swiss [[pharmaceutical]] company. According to some research,<ref>Fletcher, A., and Shepherd, R. Use of (+)-mefloquine for the treatment
  13 KB (1,807 words) - 16:41, 27 September 2010
• Chloroquine
  ...ificant therapeutic value as an anti-malarial drug. It was introduced into clinical practice in 1947 for the prophylactic treatment of malaria.<ref>http://www. * Chloroquine is in clinical trials as an investigational [[antiretroviral]] in humans with [[AIDS|HIV-1
  16 KB (2,187 words) - 16:41, 27 September 2010
• Dexamethasone
  ...erative removal of impacted third molar teeth |journal=European Journal of Clinical Pharmacology |volume=44 |issue=3 |pages=275–277 |year=2004 |pmid= 8491244 ...ino T, Ichijo T, Chrousos GP |title=Generalized glucocorticoid resistance: clinical aspects, molecular mechanisms, and implications of a rare genetic disorder
  18 KB (2,498 words) - 16:41, 27 September 2010
• Acetylcysteine
  ==Clinical use== ...s a reason for the low [[bioavailability]] of ''N''-acetylcysteine. In the research conducted by Baker,<ref name = dilger/> it was concluded that oral N-acetyl
  28 KB (3,682 words) - 16:42, 27 September 2010
• Naloxone
  <!--Clinical data--> ...].<ref>{{cite book|last1=Roberts|first1=James R.|title=Roberts and Hedges' clinical procedures in emergency medicine|date=2014|publisher=Elsevier Health Scienc
  33 KB (4,541 words) - 10:57, 17 June 2016
• Praziquantel
  Praziquantel was developed in the laboratories for parasitological research of [[Bayer AG]] and [[Merck KGaA]] in Germany (Elberfeld and Darmstadt) in ...l.<ref>{{cite journal |author=Quinn DI, Day RO |title=Drug interactions of clinical importance. An updated guide |journal=Drug Saf |volume=12 |issue=6 |pages=3
  12 KB (1,580 words) - 16:42, 27 September 2010
• Chloramphenicol
  Although unpublished, recent research suggests that chloramphenicol could also be applied to frogs to prevent the Chinese research shows that chloramphenicol affects motor neurones. It also affects insulin
  29 KB (3,876 words) - 16:42, 27 September 2010
• Doxycycline
  ...ff A, Massung RF, Christensson B |title=Human granulocytic ehrlichiosis--a clinical case in Scandinavia |journal=Scand. J. Infect. Dis. |volume=33 |issue=1 |pa ...th renal impairment.<ref>{{cite web |author=Center for Drug Evaluation and Research |title=European recommendations on the use of oral antibiotics for acne |ur
  20 KB (2,578 words) - 16:43, 27 September 2010
• Metronidazole
  ...a possible carcinogen according to the [[WHO]] [[International Agency for Research on Cancer]] (IARC).<ref> |work=International Agency for Research on Cancer (IARC)
  19 KB (2,528 words) - 16:43, 27 September 2010
• Vancomycin
  ==Clinical use== |title=Serum vancomycin concentrations: reappraisal of their clinical value
  31 KB (4,198 words) - 16:43, 27 September 2010
• Pyrazinamide
  ...Organisation|WHO]] recommend its use in pregnancy; and there is extensive clinical experience to show that it is safe. In the U.S., pyrazinamide is not used --><ref name="MRC">{{cite journal | author=Hong Kong Chest Service, Medical Research Council | title=Controlled trial of four thrice weekly regimens and a daily
  12 KB (1,557 words) - 16:44, 27 September 2010
• Streptomycin
  ...nst pulmonary tuberculosis was carried out in 1947 by the MRC Tuberculosis Research Unit. Whilst neither [[Blind experiment|double-blind]] nor [[placebo|placeb ...hange in scientific approach: from alternation to randomised allocation in clinical trials in the 1940s
  9 KB (1,069 words) - 15:06, 6 July 2010
• Cycloserine
  ...f |accessdate=2008-07-15 |doi=10.1111/j.0963-7214.2005.00367.x}}</ref>), [[clinical depression|depression]], [[obsessive-compulsive disorder]] and [[schizophre Recent research suggests that D-cycloserine (d-4-amino-3-isoxazolidone) may be effective in
  5 KB (602 words) - 16:44, 27 September 2010
• Fluconazole
  ==Clinical use== ...als Using a High Throughput Aromatase Inhibition Assay | journal=Endocrine Research | volume=28 | issue=3 | pages=129 | year=2002 | pmid=12489563 | doi=10.1081
  11 KB (1,533 words) - 16:44, 27 September 2010
• Amphotericin B
  ...a|filamentous]] [[bacterium]], in 1955 at the Squibb Institute for Medical Research from cultures of an undescribed streptomycete isolated from the soil collec ...d Richard T. liposomal formulation, structure, mechanism of action and pre-clinical experience. Journal of Antimicrobial Chemotherapy (2002) 49, 21-30</ref> Th
  13 KB (1,785 words) - 16:44, 27 September 2010
• Lamivudine
  ...discovered accidentally when a patient took Zidovudine secretly while in a clinical trial of Lmivudine monotherapy. Dr. Yung-Chi Cheng of [[Yale University]] ...lly, and it is rapidly absorbed with a bio-availability of over 80%. Some research suggests that lamivudine can cross the [[blood-brain barrier]]. Lamivudine
  9 KB (1,248 words) - 16:44, 27 September 2010
• Stavudine
  ...ntly reconsidered as an anti-HIV agent by the [[Rega Institute for Medical Research]] in [[Belgium]]. Stavudine was approved by the U.S. [[Food and Drug Admini ...Stavudine has been shown in laboratory test to be [[genotoxic]], but with clinical doses its [[carcinogen]]ic effects are non-existent. It is also one of the
  4 KB (574 words) - 16:44, 27 September 2010
• Tenofovir
  ...(IOCB) in [[Prague]], and [[Erik DeClercq]], [[Rega Institute for Medical Research]], [[Katholieke Universiteit Leuven|Catholic University of Leuven]], [[Belg ...s. There are no study results demonstrating the effect of tenofovir on the clinical progression of HIV.
  6 KB (871 words) - 16:45, 27 September 2010
• Lopinavir
  ...adiation light source at [[Argonne National Laboratory]]. One of the early research projects undertaken at the Advanced Photon Source was the Human Immunodefic | title = Research at Argonne helps Abbott Labs develop anti-HIV drug
  8 KB (1,109 words) - 16:45, 27 September 2010

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