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...RB, Herzenberg LA | title = High-dose oral N-acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis | journal = [[PNAS]] | year = 20 ...79% in the placebo group developed symptoms.<ref>{{cite journal |author=S. De Flora, C. Grassi, L. Carati |title=Attenuation of influenza-like symptomato

--><ref>{{cite journal | author = Mulhall A, de Louvois J, Hurley R | title = Chloramphenicol toxicity in neonates: its inc ...This creates a problem: chloramphenicol succinate ester is an inactive [[prodrug]] and must first be hydrolysed to chloramphenicol; the hydrolysis process i

...d it is today commonly known as EES (erythromycin ethylsuccinate, an ester prodrug that is commonly administered). [[de:Erythromycin]]

...also been shown to be important in the action of another antimycobacterial prodrug [[PA-824]].<ref>{{Cite journal|author=Singh R, Manjunatha U, Boshoff HI, '' [[de:Isoniazid]]

Pyrazinamide is a [[prodrug]] that stops the growth of ''[[Mycobacterium tuberculosis]]''. [[de:Pyrazinamid]]

...ef name="pmid11823459">{{cite journal |author=Vannelli TA, Dykman A, Ortiz de Montellano PR |title=The antituberculosis drug ethionamide is activated by [[de:Ethionamid]]

| last = de Clercq | first = Erik | last2 = Field | first2 = Hugh J | title = Antiviral prodrugs &mdash; the development of successful prodrug strategies for antiviral chemotherapy

Tenofovir disoproxil fumarate is a [[prodrug]] form of Tenofovir. Tenofovir is also available in a fixed-dose combinatio [[de:Tenofovir]]

| metabolism = Metabolized to 5'phosphates, de-riboside, and deriboside carboxylic acid ...or [[peginterferon alfa-2a]]) and other viral infections. Ribavirin is a [[prodrug]], which when metabolised resembles [[purine]] [[RNA]] [[nucleotide]]s. In

...opium was used in diverse preparations known as [[laudanum]] (see [[Thomas de Quincey]]'s "[[Confessions of an English Opium-Eater]]", 1821) and [[parego Codeine is considered a [[prodrug]], since it is metabolised ''[[in vivo]]'' to the primary active compounds

...j.1365-2036.2000.00788.x}}</ref> [[Clopidogrel]] (Plavix) is an inactive [[prodrug]] that partially depends on CYP2C19 for conversion to its active form; inhi [[de:Omeprazol]]

As a [[prodrug]], enalapril is metabolised ''in vivo'' to the active form enalaprilat by v Enalapril is a prodrug that is converted by deesterification to converting enzyme inhibitor, enala

--><ref>{{cite journal | author=De Clercq E | title=HIV resistance to reverse transcriptase inhibitors. | jour ...bolism of CycloSaligenyl 3'-azido-2', 3'-dideoxythymidine monophosphate, a prodrug of 3'-azido-2', 3'-dideoxythymidine (zidovudine). | journal=Mol Pharmacol |

...nalog of [[enalapril]]. Unlike other ACE inhibitors, lisinopril is not a [[prodrug]] and is excreted unchanged in the urine. In cases of [[Effective dose|over [[de:Lisinopril]]

...tential to participate in the carbon cycle via microbiologically catalyzed de-esterification and decomposition of the resulting cellulose and organic aci ...urizing properties. Using chitin and chitosan as carriers, a water-soluble prodrug has been synthesized. Modified chitosans have been prepared with various ch

...anafax DM |title=Clinical pharmacokinetics of XP13512, a novel transported prodrug of gabapentin |journal=Journal of Clinical Pharmacology |volume=48 |issue=1

...]). This is the same route that is used to convert many different opiate [[prodrug]]s into the active form. The proportion of drug that is converted into the * [[Hydrocodone]] - a hepatic prodrug of hydromorphone

...ame="pmid19238739">{{cite journal | author = Schwartz AR, Pizon AF, Brooks DE | title = Dextromethorphan-induced serotonin syndrome | journal = Clinical ...he NMDA receptor itself, it is likely that dextromethorphan functions as a prodrug to its nearly 10-fold more potent metabolite dextrorphan, and this is the t

A water-soluble [[prodrug]] form, [[fospropofol]], has recently been developed and tested with positi [[de:Propofol]]

...nt l’etude experimentale de l’emploi clinique du gamma hydroxybutyrate de Na | journal = Aggressologie | volume = 1 | page =407 | language = French| ...h as [[baclofen]] and [[phenibut]].<ref>{{cite journal |author=Smolders I, De Klippel N, Sarre S, Ebinger G, Michotte Y |title=Tonic GABA-ergic modulatio