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• Ivermectin
  ...nable to afford the drug <ref>http://www.mectizan.org/about.asp</ref>. The disease is endemic in 30 African countries, 6 Latin American countries and Yemen, a ..., the [[Smooth Collie]] and the [[Australian Shepherd]]) are affected by a genetic defect, a mutation within the MDR1 gene. Affected dogs are very sensitive t
  10 KB (1,292 words) - 16:41, 27 September 2010
• Chloroquine
  ...with chloroquine alone, but is no longer recommended by the [[Centers for Disease Control and Prevention|CDC]] due to the availability of more effective comb ...ted to the malaria parasite load in blood. There is evidence that it has a genetic basis and is related to chloroquine action with opiate receptors centrally
  16 KB (2,187 words) - 16:41, 27 September 2010
• Dexamethasone
  ...asone is used to treat many [[inflammation|inflammatory]] and [[autoimmune disease|autoimmune]] conditions, such as [[rheumatoid arthritis]].
  18 KB (2,498 words) - 16:41, 27 September 2010
• Deferoxamine
  ...eat [[hemochromatosis]], a disease of iron accumulation that can be either genetic or acquired. Acquired [[hemochromatosis]] is common in patients with certai
  5 KB (714 words) - 20:14, 21 September 2010
• Dimercaprol
  ...of BAL (2,3-dimercaptopropanol) on hepatolenticular degeneration (Wilson's disease) |journal=N. Engl. J. Med. |volume=245 |issue=24 |pages=917–25 |year=1951
  5 KB (644 words) - 20:14, 21 September 2010
• Penicillamine
  * In [[Wilson's disease]], a rare genetic disorder of [[copper]] metabolism, penicillamine treatment relies on its bi ...stic-anemia (idiosyncratic) <ref>Robbins and Cotran, Pathological Basis of Disease 8th Edition, Kumar et al</ref>
  5 KB (570 words) - 20:14, 21 September 2010
• Chloramphenicol
  ...hi/science/nature/7067613.stm BBC News]</ref> Chytridiomycosis is a fungal disease, blamed for the extinction of one-third of the 120 frog species lost since ...months after chloramphenicol treatment has been stopped and there may be a genetic predisposition.<ref>{{cite journal | doi = 10.1056/NEJM196907032810102 | au
  29 KB (3,876 words) - 16:42, 27 September 2010
• Abacavir
  ...ct is [[hypersensitivity]], which can be severe, and in rare cases, fatal. Genetic testing can indicate whether an individual will be hypersensitive; over 90% ...ct Dis | author=Rauch A, Nolan D, Martin A, ''et al.'' | title=Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in
  8 KB (1,124 words) - 16:44, 27 September 2010
• Ribavirin
  ...of ribavirin is [[hemolytic anemia]], which may worsen preexisting cardiac disease. The mechanism for this effect is unknown. It is dose-dependent and may som ...nucleoside]] antimetabolite drugs that interfere with duplication of viral genetic material. Though not effective against all viruses, ribavirin is remarkable
  23 KB (3,222 words) - 16:45, 27 September 2010
• Valproic acid
  ...in a study doses of valproic acid reversed the early stages of Alzheimer's disease in mice. Human trials are underway.{{Citation needed|date=June 2010}} ...ws for reprogramming of human fibroblasts to iPS cells without addition of genetic factors ''[[Klf4]]'' and ''[[c-myc]]''. This function has also been invest
  25 KB (3,328 words) - 16:47, 27 September 2010
• Aspirin
  ...t al.'' |title=Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised ....2% to 6.7% of such events per year for people already with cardiovascular disease. Although aspirin also raises the risk of [[Stroke#Hemorrhagic_stroke|hemor
  78 KB (10,918 words) - 16:52, 27 September 2010
• Azathioprine
  ...tis]], [[atopic dermatitis]], [[Myasthenia Gravis]] and [[restrictive lung disease]]. ...ransferase]] (TPMT) deactivates 6-mercaptopurine. [[Polymorphism (biology)|Genetic polymorphism]]s of TPMT can lead to excessive drug toxicity, thus assay of
  11 KB (1,410 words) - 16:49, 27 September 2010
• Cortisol
  ...he jejunum. Perfusion studies in normal subjects and patients with coeliac disease |journal=Scand. J. Gastroenterol. |volume=16 |issue=5 |pages=667–71 |year ...he pain in rheumatoid arthritis since cell potassium is always low in that disease <ref>LaCelle PL et al. (1964) “An investigation of total body potassium i
  41 KB (5,644 words) - 16:50, 27 September 2010
• Zidovudine
  ...Company]] (now GlaxoSmithKline) began searching for compounds to treat the disease. Burroughs-Wellcome had expertise in viral diseases, led by researchers inc ...does not destroy the HIV infection, but only delays the progression of the disease and the replication of virus, even at very high doses. During prolonged AZ
  21 KB (3,049 words) - 16:51, 27 September 2010
• Morphine
  .../www.amusingfacts.com/facts/Detail/soldiers-disease-morphine.html Soldiers Disease A Historical Hoax?]</ref> ...of drug abuse, specifically morphine and [[heroin]], on progression of the disease. The discovery of such an association would impact treatment of both HCV in
  87 KB (12,376 words) - 16:51, 27 September 2010
• Paracetamol
  ...acetamol toxicity are believed to be due to a third isoenzyme, [[CYP2D6]]. Genetic polymorphisms in [[CYP2D6]] may contribute to significantly different rates ...ation", i.e., that the association may not be causal but rather due to the disease being treated with paracetamol, and emphasized that further research is nee
  54 KB (7,376 words) - 16:52, 27 September 2010
• Locoweed
  ...39.</ref> '''swainsonine toxicosis''', '''locoweed disease''', and '''loco disease'''; North America) and '''pea struck'''<ref name="pmid2110378">{{cite journ ...oweed (and little else) develop a [[lysosomal storage disease]] similar to genetic [[mannosidosis]].<ref name="pmid10091126">{{cite journal
  18 KB (2,369 words) - 12:27, 7 July 2010
• Atropa belladonna
  ...ortment of conditions including headache, menstrual symptoms, peptic ulcer disease, histaminic reaction, inflammation, and motion sickness,<ref name="medline" ...cite web | title=Compounds in deadly nightshade | work=USDA, ARS, National Genetic Resources Program. Phytochemical and Ethnobotanical Databases|publisher=Nat
  24 KB (3,421 words) - 12:28, 7 July 2010
• Depleted uranium
  ...e because of its long [[half-life]]. The [[Agency for Toxic Substances and Disease Registry]] states that: "to be exposed to radiation from uranium, you have |author= [[Agency for Toxic Substances and Disease Registry]]
  80 KB (11,721 words) - 10:13, 20 September 2010
• Hemp
  ...h they can also be distinguished genetically.<ref>Datwyler SL, Weiblen GD. Genetic Variation in Hemp and marijuana (''Cannabis sativa L.'') ''sativa'' plants ...ontains no [[gluten]] and therefore would not trigger symptoms of [[celiac disease]].
  42 KB (6,310 words) - 22:11, 21 September 2010

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