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...II production. Angiotensin II increases blood pressure by stimulating the Gq protein in vascular smooth muscle cells (which in turn activates contractio ...herosclerosis, or endothelial damage. Angiotensin II is the most important Gq stimulator of the heart during hypertrophy, compared to endothelin-1 and A1

|rowspan=2| Activation of [[gi alpha subunit|G_i]] --> ↓[[cyclic adenosine monophosphate|cAMP]] --> ↓[[pro |rowspan=3| Activation of [[gq alpha subunit|G_q]] --> ↑[[phospholipase C|PLC]] activity --> ↑[[Inositol t

|rowspan=5| ↑[[Gs alpha subunit|G_s]] activity --> ↑[[adenylate cyclase|AC]] activity --> ↑[[ ...| [[Vasoactive intestinal peptide receptor|VIP receptor]] || ↑[[Gs alpha subunit|G_s]] activity --> ↑[[adenylate cyclase|AC]] activity --> ↑[[