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...creases its function. This causes an increase in the level of [[sodium]] [[ion]]s in the myocytes, which then leads to a rise in the level of [[calcium]] ...l flutter]] with rapid ventricular response, but beta- or calcium channel- blockers should be the first choice [http://circ.ahajournals.org/cgi/content/full/10

...es act via [[micromolar]] benzodiazepine binding sites as [[Ca2+]] channel blockers and significantly inhibit depolarization-sensitive Calcium uptake in rat ne ...e enhanced. Benzodiazepines cause an increased opening of the chloride ion channel when GABA binds to its site on the GABA_A receptor leading to mor

...ed primarily as a research tool, in characterizing subtypes of [[potassium channel]], and has also been used to manage some of the symptoms of [[multiple scle ...idine is as a precursor to the drug [[pinacidil]], which affects potassium ion channels.

...oving the stimulus for contraction, which depends on intracellular calcium ion concentrations and, consequently, [[phosphorylation]] of the light chain of | [[Hyperpolarization]] mediated ([[Calcium channel blocker]])

...fairly straightforward mechanism. A substantial and rapid rise in calcium ion concentration inside the postsynaptic cell (or more specifically, within th ...MPAR channel, thus causing only a small [[depolarization]]. The open AMPAR channel is often considered to be non-calcium permeable, but this is only an approx

...rg/cgi/content/abstract/868/1/370 }}</ref> SK channels are a type of [[ion channel]] allowing [[potassium]] cations to cross the cell membrane and are activat ...loop between the fifth and sixth trans membrane domain forms the potassium ion [[potassium_channel#Selectivity_filter|selectivity filter]].

...rimarily in biomedical research to study the electrical properties of [[SK channel]]s and their role in the after [[Hyperpolarization (biology)|hyperpolarizat ....bmc.2007.05.054 | url = | issn = }}</ref> It inhibits the three cloned SK channel subtypes (SK1, SK2, and SK3) with different affinity, highest affinity for

| Name = Neurotransmitter-gated ion-channel transmembrane region | caption = Ligand-gated ion channel