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  • '''Abacavir''' ('''ABC''') is a [[nucleoside]] analog [[reverse transcriptase inhibitor]] (NRTI) used to treat [[HIV]] and [[AIDS]]. It is available unde ...nalog]] of [[guanosine]] (a [[purine]]). Its target is the viral [[reverse transcriptase]] enzyme.
    8 KB (1,124 words) - 16:44, 27 September 2010
  • ...ld under the trade names '''Videx''' and '''Videx EC'''. It is a [[reverse transcriptase inhibitor]], effective against [[HIV]] and used in combination with other [ ...t acts as a chain terminator by incorporation and inhibits viral [[reverse transcriptase]] by competing with natural [[Adenosine triphosphate|dATP]].
    9 KB (1,239 words) - 16:44, 27 September 2010
  • ...me '''Emtriva''' (formerly '''Coviracil'''), is a [[nucleoside]] [[reverse transcriptase inhibitor]] (NRTI) for the treatment of [[HIV]] infection in adults and chi ...mistry)|analogue]] of [[cytidine]]. The drug works by inhibiting [[reverse transcriptase]], the enzyme that copies HIV RNA into new viral DNA. By interfering with t
    5 KB (667 words) - 16:44, 27 September 2010
  • ...') is a potent [[reverse transcriptase inhibitor|nucleoside analog reverse transcriptase inhibitor]] (nRTI). ...approval process switched to [[protease inhibitor (pharmacology)|protease inhibitors]]. According to the manufacturer's 2004 annual report, its patent will expi
    9 KB (1,248 words) - 16:44, 27 September 2010
  • ...Zerit''') is a [[Reverse transcriptase inhibitor|nucleoside analog reverse transcriptase inhibitor]] (NARTI) active against [[HIV]]. ...to active triphosphate. Stavudine triphosphate inhibits the HIV [[reverse transcriptase]] by competing with natural substrate, thymidine triphosphate. It also cau
    4 KB (574 words) - 16:44, 27 September 2010
  • ...alogue [[reverse transcriptase inhibitor]]s (nRTIs), which block [[reverse transcriptase]], an enzyme crucial to viral production in [[HIV]]-infected people. In July 2010, a vaginal gel containing [[tenofovir]], a [[reverse transcriptase inhibitor]], was shown to reduce HIV infection rates by 39 percent in a tri
    6 KB (871 words) - 16:45, 27 September 2010
  • ...l drug]] used for the treatment of HIV/AIDS. It is an [[analog (chemistry)|analog]] of [[thymidine]]. ...rch efforts focused on the viral enzyme [[reverse transcriptase]]. Reverse transcriptase is an enzyme that retroviruses, including HIV, utilize to replicate themsel
    21 KB (3,049 words) - 16:51, 27 September 2010