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{{Main|Olney's lesions}}

...as been demonstrated to produce [[neurotoxicity]] in the form of [[Olney's lesions]] (damage to the [[posterior cingulate]] and [[retrosplenial region|retrosp

...tagonist]]s could stop the neurotoxicity.<ref name="Olney">Olney JW. Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate.

...the relationship between rat brain metabolism and the creation of Olney's Lesions has been discredited and may not apply to humans, as has been shown with ke

...performed on rats, giving them 50mg and up every day up to a month. Small lesions were believed to be found during the autopsy on the brain. However the only