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...at it has a genetic basis and is related to chloroquine action with opiate receptors centrally or peripherally.<ref>{{cite journal |author=Ajayi AA |title=Mecha ...times the rate of CQ-Sensitive cells; the related mutations trace back to transmembrane proteins of the digestive vacuole, including sets of critical mutations in

...arnett-Norris J, Reggio PH, Song ZH |title=Cysteine 2.59(89) in the second transmembrane domain of human CB2 receptor is accessible within the ligand binding crevic

...beta, gamma or delta subunits (some consist of 5 alpha subunits). Cys-loop receptors possess a characteristic loop formed by a disulfide bond between two [[cyst ...a cytoplasmic loop of variable size and amino acid sequence; and a fourth transmembrane domain with a relatively short and variable extracellular C terminal. All

...processing have invited comparisons to the signaling role of the surface [[transmembrane receptor|receptor]] protein [[Notch signaling|Notch]].<ref name="Selkoe">{{ ...e=Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein |journal=J. Biol. Chem. |volume=273 |issu

K_Ca2.3 contains 6 [[transmembrane domain]]s, a pore-forming region, and intracellular [[N-terminus|N]]- and [ ...l |author=Gao Y, Chotoo CK, Balut CM, ''et al.'' |title=Role of S3 and S4 transmembrane domain charged amino acids in channel biogenesis and gating of KCa2.3 and K

...(CNBD) in the C-terminus. HCN isoforms are highly conserved in their core transmembrane regions and cyclic nucleotide binding domain (80–90% identical), but dive ...authorlink = | coauthors = | date = | format = | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Ph

...as testosterone, can pass through the cell membrane, and bind directly to receptors in the cytoplasm or nucleus. ...hin the [[cytoplasm]], and usually act by stimulating the binding of their receptors to the [[promotor (biology)|promoter region]] of steroid-responsive [[genes

...I-IV) each comprising six transmembrane segments (S1-S6) for a total of 24 transmembrane segments. The members of this family also coassemble with auxiliary β subu ...e cell membrane following [[action potential]]s. The α subunits have six transmembrane segments, homologous to a single domain of the sodium channels. Correspond

| Name = Neurotransmitter-gated ion-channel transmembrane region ...of ionotropic receptor or channel-linked receptor. They are a group of [[transmembrane]] [[ion channel]]s that are opened or closed in response to the binding of

...of which have been shown to bind ethylene. [[DNA]] sequences for ethylene receptors have also been identified in many other plant species and an ethylene bindi