Streptolydigin

From Self-sufficiency
Jump to: navigation, search
Streptolydigin
File:Streptolydigin.png
Systematic (IUPAC) name
2-[4-[6-(1,6-dimethylspiro[8,9-dioxabicyclo[3.3.1]non-3-ene-2,2'-oxirane]-7

-yl)-4-methylhepta-2,4-dienoyl]-5-hydroxy-1-(5-hydroxy-6-methyloxan-2-yl)-3

-oxo-2H-pyrrol-2-yl]-N-methylpropanamide
Identifiers
CAS Number 7229-50-7
ATC code none
PubChem CID 220508
Chemical data
Formula C32H44N2O9
Molar mass 600.708 g/mol[[Script error: No such module "String".]]
Script error: No such module "TemplatePar".Expression error: Unexpected < operator.

Streptolydigin is an antibiotic which works by blocking nucleic acid chain elongation by binding to the polymerase, thus stopping RNA polymerase activity inside a cell. Specifically, it inhibits the assembly of the RNA polymerase II transcription complex and DNA polymerase III transcription. It is active against a number of gram positive bacteria.