TDIQ

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TDIQ
File:TDIQ structure.png
Systematic (IUPAC) name
5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline
Identifiers
CAS Number 15052-05-8
PubChem CID 2752332
Chemical data
Formula C10H11NO2
Molar mass 177.199[[Script error: No such module "String".]]
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TDIQ (also known as 6,7-Methylenedioxy-1,2,3,4-tetrahydroisoquinoline or MDTHIQ) is a drug used in scientific research, which has anxiolytic and anorectic effects in animals.[1][2] It has an unusual effects profile in animals, with the effects generalising to cocaine and partially to MDMA and ephedrine,[3] but the effects did not generalise to amphetamine and TDIQ does not have any stimulant effects.[4] It is thought these effects are mediated via a partial agonist action at Alpha-2 adrenergic receptors, and TDIQ has been suggested as a possible drug for the treatment of cocaine dependence.[5]

See also

References

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  1. ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
  2. ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
  3. ↑ Young R, Glennon RA (2002). "The stimulus effect of 5,6,7,8-tetrahydro-1,3-dioxolo[4,5-g]isoquinoline is similar to that of cocaine but different from that of amphetamine". Pharmacology, Biochemistry, and Behavior. 71 (1-2): 205–13. doi:10.1016/S0091-3057(01)00666-9. PMID 11812524. 
  4. ↑ Lua error in package.lua at line 80: module 'Module:Citation/CS1/Suggestions' not found.
  5. ↑ Young R (2007). "TDIQ (5,6,7,8-tetrahydro-1,3-dioxolo [4,5-g]isoquinoline): discovery, pharmacological effects, and therapeutic potential". CNS Drug Reviews. 13 (4): 405–22. doi:10.1111/j.1527-3458.2007.00022.x. PMID 18078426. 
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