Table of volume of distribution for drugs
From Self-sufficiency
This is a table of volume of distribution (Vd) for various medication. For comparison, those with a Vd/kg body weight of less than 0.2 are mainly distributed in blood plasma, 0.2-0.7 mostly in the extracellular fluid and those with more than 0.7 are distributed throughout total body water.
Medication | Vd / kg body weight |
---|---|
heparin | 0.05-0.1[1] |
insulin | 0.05-0.1[1] |
warfarin | 0.1-0.2[1] |
sulfamethoxazole | 0.1-0.2[1] |
glibenclamide | 0.1-0.2[1] |
atenolol | 0.1-0.2[1] |
NXY-059 | 0.1-0.2[2] |
tubocurarine | 0.2-0.4[1] |
theophylline | 0.4-0.7[1] |
ethanol | 0.7-0.9[1] |
neostigmine | 0.7-0.9[1] |
phenytoin | 0.7-0.9[1] |
methotrexate | 1-2[1] |
indometacin | 1-2[1] |
paracetamol | 1-2[1] |
diazepam | 1-2[1] |
lidocaine | 1-2[1] |
glyceryl nitrate | 2-5[1] |
morphine | 2-5[1] |
propranolol | 2-5[1] |
digoxin | 2-5[1] |
chlorpromazine | 2-5[1] |
nortriptyline | 2-5[1] |
chloroquine | 200[2] |