Talarozole
From Self-sufficiency
| File:R115866 structure.svg | |
| Systematic (IUPAC) name | |
|---|---|
|
N-(2-Benzothioazolyl)-N-[4-[2-ethyl-1-(1,2,4-triazo-1-yl)butyl]phenyl]amine | |
| Clinical data | |
| Routes of administration | oral, topical |
| Identifiers | |
| CAS Number | 201410-53-9 |
| ATC code | none |
| PubChem | CID 9799888 |
| Chemical data | |
| Formula | C21H23N5S |
| Molar mass | 377.505 g/mol[[Script error: No such module "String".]] |
| Script error: No such module "collapsible list". | |
Talarozole (formerly R115866, planned trade name Rambazole) is an investigational drug for the treatment of acne, psoriasis and other keratinization disorders.
Talarozole inhibits the metabolism of retinoic acid by blocking the cytochrome P450 enzyme isoform CYP26, a retinoic acid hydroxylase. Because of this mechanism, it is called a retinoic acid metabolism blocking agent (RAMBA).[1]
References
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