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Sevcik, J; Nieber, K; Driessen, B; Illes, P (1993). "Effects of the central analgesic tramadol and its main metabolite, O-desmethyltramadol, on rat locus coeruleus neurones". British journal of pharmacology. 110 (1): 169–76. PMC 2175982 Freely accessible. PMID 8220877. 

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