Template:PBB/2149

Coagulation factor II (thrombin) receptor
Identifiers
Symbols	F2R; CF2R; HTR; PAR1; TR
External IDs	OMIM: 187930 MGI: 101802 HomoloGene: 1510 IUPHAR: PAR1 GeneCards: F2R Gene
Gene Ontology Molecular function • rhodopsin-like receptor activity • receptor activity • receptor binding • thrombin receptor activity Cellular component • Golgi apparatus • plasma membrane • integral to plasma membrane Biological process • regulation of progression through cell cycle • apoptosis • caspase activation • cell motility • signal transduction • G-protein coupled receptor protein signaling pathway • tyrosine phosphorylation of STAT protein • STAT protein nuclear translocation • multicellular organismal development • blood coagulation • response to wounding • anatomical structure morphogenesis • positive regulation of I-kappaB kinase/NF-kappaB cascade Sources: Amigo / EGO
RNA expression pattern
250px
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2149	14062
Ensembl	ENSG00000181104	ENSMUSG00000048376
UniProt	P25116	Q3UK34
RefSeq (mRNA)	NM_001992	NM_010169
RefSeq (protein)	NP_001983	NP_034299
Location (UCSC)	Chr 5: 76.05 - 76.07 Mb	Chr 13: 96.7 - 96.72 Mb
PubMed search	[1]	[2]