Template:PBB/2346

Folate hydrolase (prostate-specific membrane antigen) 1
250px Model of the glutamate carboxypeptidase II enzyme, based on Protein Data Bank structure 2oot.
Available structures PDB 1z8l, 2c6c, 2c6g, 2c6p, 2cij, 2jbj, 2jbk, 2oot, 2pvv, 2pvw
Identifiers
Symbols	FOLH1; PSM; FGCP; FOLH; GCP2; GCPII; NAALAD1; NAALAdase; PSMA; mGCP
External IDs	OMIM: 600934 MGI: 1858193 HomoloGene: 121694 GeneCards: FOLH1 Gene
EC number	3.4.17.21
Gene Ontology Molecular function • carboxypeptidase activity • metallopeptidase activity • zinc ion binding • dipeptidase activity • glutamate carboxypeptidase II activity • metal ion binding Cellular component • membrane fraction • integral to plasma membrane • membrane Biological process • proteolysis Sources: Amigo / EGO
RNA expression pattern
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More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2346	53320
Ensembl	ENSG00000086205	ENSMUSG00000001773
UniProt	Q04609	O35409
RefSeq (mRNA)	NM_001014986	NM_016770
RefSeq (protein)	NP_001014986	NP_058050
Location (UCSC)	Chr 11: 49.12 - 49.19 Mb	Chr 7: 93.87 - 93.92 Mb
PubMed search	[1]	[2]